J. Hackett

Publications43
h-index29
Citations8,014
Highly Influential Citations653
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Genome sequence of enterohaemorrhagic Escherichia coli O157:H7
TLDR
It is found that lateral gene transfer is far more extensive than previously anticipated and 1,387 new genes encoded in strain-specific clusters of diverse sizes were found in O157:H7, including candidate virulence factors, alternative metabolic capacities, several prophages and other new functions—all of which could be targets for surveillance.
A molecular timeline for the origin of photosynthetic eukaryotes.
TLDR
An ancient (late Paleoproterozoic) origin of photosynthetic eukaryotes with the primary endosymbiosis that gave rise to the first alga having occurred after the split of the Plantae from the opisthokonts sometime before 1,558 MYA is supported.
Extensive mosaic structure revealed by the complete genome sequence of uropathogenic Escherichia coli
TLDR
The complete genome sequence of uropathogenic Escherichia coli, strain CFT073 is presented and Comparisons indicate that extraintestinal pathogenic E. coli arose independently from multiple clonal lineages.
Phylogenomic analysis supports the monophyly of cryptophytes and haptophytes and the association of rhizaria with chromalveolates.
TLDR
Maximum likelihood and Bayesian analyses of phylogenomics with expressed sequence tag data from the ecologically important coccolithophore-forming alga Emiliania huxleyi and the plastid-lacking cryptophyte Goniomonas cf.
A single origin of the peridinin- and fucoxanthin-containing plastids in dinoflagellates through tertiary endosymbiosis
TLDR
It is postulated that the plastid of peridinin- and fucoxanthin-containing dinoflagellates originated from a haptophyte tertiary endosymbiosis that occurred before the split of these lineages.
Dinoflagellates: a remarkable evolutionary experiment.
TLDR
This chapter reviews the current knowledge of gene regulation and transcription in dinoflagellates with regard to the unique aspects of the nuclear genome and the implications for understanding organellar genome evolution are discussed.
Insights into a dinoflagellate genome through expressed sequence tag analysis
TLDR
This is the most extensive collection to date of ESTs from a toxic dinoflagellate and will be instrumental to future research to understand the unique and complex cell biology of these organisms and for potentially identifying the genes involved in toxin production.
Photosynthetic eukaryotes unite: endosymbiosis connects the dots.
TLDR
Algal diversity is examined and endosymbiosis is shown to be a major force in algal evolution, with long-standing issues such as the chromalveolate hypothesis and the extent of endOSymbiotic gene transfer clarified.
The Single, Ancient Origin of Chromist Plastids
TLDR
Here a taxonomically diverse group of chlorophyll are analyzed to show that a taxonomicically diversegroup ofchlorophyll is represented in algal lineages with complex evolutionary history involving a secondary en-dosymbiotic event.
Triassic origin and early radiation of multicellular volvocine algae
TLDR
Estimating divergence times using a multigene data set with multiple fossil calibrations and using these estimates to infer the times of developmental changes relevant to the evolution of multicellularity show that Volvox diverged from unicellular ancestors at least 200 million years ago.
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