J. Hackett

Publications59
h-index26
Citations6,248
Highly Influential Citations562
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Genome sequence of enterohaemorrhagic Escherichia coli O157:H7
The bacterium Escherichia coli O157:H7 is a worldwide threat to public health and has been implicated in many outbreaks of haemorrhagic colitis, some of which included fatalities caused by haemolytic… Expand
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A molecular timeline for the origin of photosynthetic eukaryotes.
The appearance of photosynthetic eukaryotes (algae and plants) dramatically altered the Earth's ecosystem, making possible all vertebrate life on land, including humans. Dating algal origin is,… Expand
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Phylogenomic analysis supports the monophyly of cryptophytes and haptophytes and the association of rhizaria with chromalveolates.
Here we use phylogenomics with expressed sequence tag (EST) data from the ecologically important coccolithophore-forming alga Emiliania huxleyi and the plastid-lacking cryptophyte Goniomonas cf.… Expand
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A single origin of the peridinin- and fucoxanthin-containing plastids in dinoflagellates through tertiary endosymbiosis
The most widely distributed dinoflagellate plastid contains chlorophyll c2 and peridinin as the major carotenoid. A second plastid type, found in taxa such as Karlodinium micrum and Karenia spp.,… Expand
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Dinoflagellates: a remarkable evolutionary experiment.
In this paper, we focus on dinoflagellate ecology, toxin production, fossil record, and a molecular phylogenetic analysis of hosts and plastids. Of ecological interest are the swimming and feeding… Expand
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Photosynthetic eukaryotes unite: endosymbiosis connects the dots.
The photosynthetic organelle of algae and plants (the plastid) traces its origin to a primary endosymbiotic event in which a previously non-photosynthetic protist engulfed and enslaved a… Expand
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Insights into a dinoflagellate genome through expressed sequence tag analysis
BackgroundDinoflagellates are important marine primary producers and grazers and cause toxic "red tides". These taxa are characterized by many unique features such as immense genomes, the absence of… Expand
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Evolution of saxitoxin synthesis in cyanobacteria and dinoflagellates.
Dinoflagellates produce a variety of toxic secondary metabolites that have a significant impact on marine ecosystems and fisheries. Saxitoxin (STX), the cause of paralytic shellfish poisoning, is… Expand
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The Single, Ancient Origin of Chromist Plastids
Algae include a diverse array of photosynthetic eukaryotes exclud-ing land plants. Explaining the origin of algal plastids continues tobe a major challenge in evolutionary biology. Current… Expand
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Origin of Saxitoxin Biosynthetic Genes in Cyanobacteria
Background Paralytic shellfish poisoning (PSP) is a potentially fatal syndrome associated with the consumption of shellfish that have accumulated saxitoxin (STX). STX is produced by microscopic… Expand
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