J. H. Fellman

Publications83
h-index21
Citations1,605
Highly Influential Citations22
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Pharmacokinetics of levodopa.
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Antioxidant role and subcellular location of hypotaurine and taurine in human neutrophils.
The subcellular location of taurine, and its precursor, hypotaurine, within human neutrophils has been examined by nitrogen cavitation, Percoll-gradient centrifugation and HPLC analysis. Hypotaurine… Expand
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Screening allergens for acrylate dermatitis associated with artificial nails
Background: Acrylates are increasingly observed to be a cause of allergic contact dermatitis (ACD), especially in the cosmetic industry. Patients suspected of acrylate allergy are generally tested to… Expand
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The metabolism of taurine to isethionate.
Abstract The biosynthesis of isethionate from taurine in mammalian tissue has been reexamined. In vivo metabolism of taurine to isethionate was demonstrated but it was shown that a number of… Expand
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Assay, properties and tissue distribution of p-hydroxyphenylpyruvate hydroxylase.
Abstract Two methods for the assay of p -hydroxyphenylpyruvate hydroxylase ( p -hydroxyphenylpyruvate, ascorbate: O 2 oxidoreductase (hydroxylating), EC 1.14.2.2) activity are described. (1) Chemical… Expand
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Purification and properties of avian liver p-hydroxyphenylpyruvate hydroxylase.
Avian liver p-hydroxyphenylpyruvate hydroxylase (EC 1.13.11.27) was purified to a 1000-fold increase in specific activity over crude supernatant, utilizing a substrate analogue,… Expand
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The oxidation of hypotaurine to taurine: bis-aminoethyl-alpha-disulfone, a metabolic intermediate in mammalian tissue.
The primary mammalian metabolic pathway leading to taurine is generally recognized as beginning with the oxidation of cysteine to cysteine sulfinate via cysteine dioxygenase (19). This rate limiting… Expand
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N-Acetylneuramin Lactose Sulfate: A Newly Identified Nutrient in Milk
ABSTRACT: The identity of a sulfate ester in rat milk has been determined to be N-acetylneuramin lactose sulfate. This sulfate ester is present in rat mammary tissue and in human milk. The presence… Expand
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The source of aromatic ketoacids in tyrosinaemia and phenylketonuria.
Abstract The studies reported here support the observation that elevated excretion of p -hydroxyphenylpyruvic acid could occur in the presence of deficient hepatic tyrosine aminotransferase activity.… Expand
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Identification of mammalian aspartate-4-decarboxylase.
Several animal tissues were examined for aspartate-4-decarboxylase (EC 4.1.1.12) activity. Highest activity was seen in murine livers, in rodent livers, and in rodent kidneys. The rat liver enzyme… Expand
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