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Biological functions of selenium and its potential influence on Parkinson's disease.
Parkinson's disease is characterized by the death of dopaminergic neurons, mainly in the substantia nigra, and causes serious locomotor dysfunctions. It is likely that the oxidative damage toExpand
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Exosomes are possibly used as a tool of immune regulation during the dendritic cell-based immune therapy against HIV-I.
Dendritic cell (DC)-based immune therapy (IT) against HIV showed variable results. It is known that different factors influence host response to DC-IT. Exosomes derived from DC are regulators of theExpand
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IL-17 blood levels increase in healthy pregnancy but not in spontaneous abortion
Cytokines are essential to maintain and coordinate the correct activity of immune cells during human pregnancy. IL-17 is a pro-inflammatory cytokine that induces the expression of many inflammatoryExpand
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CYP2B6 516 G>T polymorphism and side effects of the central nervous system in HIV-positive individuals under Efavirenz treatment: Study of a sample from southern Brazil.
This study aimed to identify the 516 G>T polymorphism of the CYP2B6 gene and evaluate its influence on central nervous system (CNS) side effect development in HIV-positive individuals undergoingExpand
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Evaluation of DNA damage in COPD patients and its correlation with polymorphisms in repair genes
BackgroundWe investigated a potential link between genetic polymorphisms in genes XRCC1 (Arg399Gln), OGG1 (Ser326Cys), XRCC3 (Thr241Met), and XRCC4 (Ile401Thr) with the level of DNA damage andExpand
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Immunogenetic studies of the hepatitis C virus infection in an era of pan-genotype antiviral therapies - Effective treatment is coming.
What are the factors that influence human hepatitis C virus (HCV) infection, hepatitis status establishment, and disease progression? Firstly, one has to consider the genetic background of the hostExpand
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Selenium reduces bradykinesia and DNA damage in a rat model of Parkinson's disease.
OBJECTIVE The aim of this study was to explore the effects of selenium (Se) on locomotor activity and DNA damage in a rat model of Parkinson's disease (PD) induced by paraquat (PQ). METHODSExpand
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DNA damage and cellular abnormalities in tuberculosis, lung cancer and chronic obstructive pulmonary disease
BackgroundTuberculosis (TB), Lung Cancer (LC) and Chronic Obstructive Pulmonary Diseases (COPD) affect millions of individuals worldwide. Monitoring of DNA damage in pathological situations has beenExpand
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Histological organization is similar in human vocal muscle and tongue--a study of muscles and nerves.
One of the most exciting questions about the human voice is how the vocal fold produces and modulates different sounds. One hypothesis to explain the wide range of movements found in the vocal foldExpand
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DNA damage and cytotoxicity in pathology laboratory technicians exposed to organic solvents.
The aim of this study was to evaluate potential DNA damage and cytotoxicity in pathology laboratory technicians exposed to organic solvents, mainly xylene. Peripheral blood and buccal cells samplesExpand
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