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Autophagy Is Essential for Mitochondrial Clearance in Mature T Lymphocytes1
TLDR
It is shown that the essential autophagy gene Atg7 is required in a cell-intrinsic manner for the survival of mature primary T lymphocytes, and mitochondrial content is developmentally regulated in T but not in B cells, with exit from the thymus marking a transition from high mitochondrial content in thymocytes to lower mitochondrial Content in mature T cells. Expand
Dynamic SDN controller assignment in data center networks: Stable matching with transfers
TLDR
This paper considers dynamic controller assignment so as to minimize the average response time of the control plane, and proposes a hierarchically two-phase algorithm that integrates key concepts from both matching theory and coalitional games to solve it efficiently. Expand
Protective role of 1,25(OH)2vitamin D3 in the mucosal injury and epithelial barrier disruption in DSS-induced acute colitis in mice
TLDR
1,25(OH)2D3 may play a protective role in mucosal barrier homeostasis by maintaining the integrity of junction complexes and in healing capacity of the colon epithelium. Expand
Genome-wide association study of 12 agronomic traits in peach
TLDR
A comprehensive genome-wide association study for 12 key agronomic traits in peach shows that among the 10 qualitative traits investigated, nine exhibit consistent and more precise association signals than previously identified by linkage analysis. Expand
Dynamin 2 Is Required for Phagocytosis in Macrophages
TLDR
Dynamin 2, a ubiquitously expressed dynamin isoform, has a role in phagocytosis in macrophages and expression of a dominant-negative mutant of dynamin 2 significantly inhibits particle internalization at the stage of membrane extension around the particle. Expand
Alternatives to vitamin B1 uptake revealed with discovery of riboswitches in multiple marine eukaryotic lineages
TLDR
It is demonstrated that one such alga, the major primary producer Emiliania huxleyi, grows on 4-amino-5-hydroxymethyl-2-methylpyrimidine (a thiamine precursor moiety) alone, although long thought dependent on exogenous sources ofThiamine, making vitamin control of phytoplankton blooms more complex than the current paradigm suggests. Expand
Integration of Chang'E-1 Imagery and Laser Altimeter Data for Precision Lunar Topographic Modeling
TLDR
Experimental results using the Chang'E-1 data in the Apollo 15 and 16 landing site areas show that the proposed combined adjustment approach can reduce the misregistrations between the imagery and the laser altimeter data by a maximum of 1-18 pixels in image space. Expand
Joint Optimization of Chain Placement and Request Scheduling for Network Function Virtualization
TLDR
To jointly optimize the performance of NFV, this work proposes a priority-driven weighted algorithm to improve resource utilization and a heuristic algorithm to reduce response latency and shows that these methods can indeed enhance performance in diverse scenarios. Expand
Effect of heat stress on expression of junction-associated molecules and upstream factors androgen receptor and Wilms' tumor 1 in monkey sertoli cells.
TLDR
Results indicate that the decreased AR expression after heat treatment is involved in heat-induced cell junction disruption and could be rescued by the AR overexpression. Expand
A Preliminary Study of the Relationship between Promoter Methylation of the ABCG1, GALNT2 and HMGCR Genes and Coronary Heart Disease
TLDR
Evidence is provided to support the association of promoter DNA methylation status with the risk profile of CHD, and the data indicates that promoter DNA hypermethylation of the ABCG1 and GALNT2 genes, but not the HMGCR gene, is associated with an increased risk ofCHD. Expand
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