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Design of experiments: an efficient strategy to identify factors influencing extraction and derivatization of Arabidopsis thaliana samples in metabolomic studies with gas chromatography/mass…
- J. Gullberg, Pär Jonsson, A. Nordström, M. Sjöström, T. Moritz
- Chemistry, Medicine
- Analytical biochemistry
- 15 August 2004
The usual aim in metabolomic studies is to quantify the entire metabolome of each of a series of biological samples. To do this for complex biological matrices, e.g., plant tissues, efficient and… Expand
A strategy for identifying differences in large series of metabolomic samples analyzed by GC/MS.
- Pär Jonsson, J. Gullberg, +4 authors T. Moritz
- Chemistry, Medicine
- Analytical chemistry
- 11 February 2004
In metabolomics, the purpose is to identify and quantify all the metabolites in a biological system. Combined gas chromatography and mass spectrometry (GC/MS) is one of the most commonly used… Expand
High-throughput data analysis for detecting and identifying differences between samples in GC/MS-based metabolomic analyses.
In metabolomics, the objective is to identify differences in metabolite profiles between samples. A widely used tool in metabolomics investigations is gas chromatography-mass spectrometry (GC/MS).… Expand
Extraction and GC/MS analysis of the human blood plasma metabolome.
Analysis of the entire set of low molecular weight compounds (LMC), the metabolome, could provide deeper insights into mechanisms of disease and novel markers for diagnosis. In the investigation, we… Expand
Airborne chemical compounds on dairy farms.
- A. Sunesson, J. Gullberg, G. Blomquist
- Environmental Science, Medicine
- Journal of environmental monitoring : JEM
The chemical environment that dairy farmers are exposed to during milking was investigated. Volatile organic compounds (VOCs) were analysed and identified, and the levels of formaldehyde, ammonia and… Expand
Cloning and Overproduction of Gibberellin 3-Oxidase in Hybrid Aspen Trees. Effects on Gibberellin Homeostasis and Development1
- M. Israelsson, E. Mellerowicz, M. Chono, J. Gullberg, T. Moritz
- Biology, Medicine
- Plant Physiology
- 1 May 2004
To broaden our understanding of gibberellin (GA) biosynthesis and the mechanism whereby GA homeostasis is maintained in plants, we have investigated the degree to which the enzyme GA 3-oxidase… Expand
Chemometrics in Metabolomics — An Introduction
Metabolomics : a tool for studying plant biology
- J. Gullberg
- 1 September 2005
In recent years new technologies have allowed gene expression, protein and metabolite profiles in different tissues and developmental stages to be monitored. This is an emerging field in plant… Expand
Metabolite Signature during Short-Day Induced Growth Cessation in Populus
The photoperiod is an important environmental signal for plants, and influences a wide range of physiological processes. For woody species in northern latitudes, cessation of growth is induced by… Expand
Global analysis of low-molecular-weight compounds in human plasma using GC/TOF-MS
We developed a method for analysis of low-molecular-weight compounds (LMWC) in human plasma involving extraction of metabolites by organic solvents, derivatization of extract and final analysis by ...