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New Molecular Considerations for Glioma: IDH, ATRX, BRAF, TERT, H3 K27M
Purpose of ReviewThis review will discuss the role of several key players in glioma classification and biology, namely isocitrate dehydrogenase 1 and 2 (IDH1/2), alpha thalassemia/mental retardationExpand
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Neuroprotective strategies and the underlying molecular basis of cerebrovascular stroke.
Stroke is a leading cause of disability in the US. Although there has been significant progress in the area of medical and surgical thrombolytic technologies, neuroprotective agents to preventExpand
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Association between Glaucoma and Obstructive Sleep Apnea Syndrome: A Meta-Analysis and Systematic Review
Background Obstructive sleep apnea syndrome (OSAS) is a common disease that increases the risk of diabetes, heart disease, and stroke. However, studies of an association between OSAS and glaucomaExpand
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Comparison of Clinical Outcomes in the National Neurosurgery Quality and Outcomes Database for Open Versus Minimally Invasive Transforaminal Lumbar Interbody Fusion
Study Design. A retrospective database review. Objective. The aim of this study was to compare data on various pain and functional outcomes for patients who underwent minimally invasiveExpand
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Clinical Outcomes with Transcranial Resection of the Tuberculum Sellae Meningioma.
BACKGROUND The tuberculum sellae is a relatively common location for meningiomas. We assessed our experience with the use of transcranial resection, which, although criticized for its more invasiveExpand
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Diagnostic Quality of Magnetic Resonance Imaging Interpretation for Peripheral Nerve Sheath Tumors: Can Malignancy Be Determined?
Background Optimal management of peripheral nerve sheath tumors including neurofibromas, schwannomas, and malignant peripheral sheath tumors (MPNSTs) is predicated on knowing the specific pathology.Expand
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Validation of the unruptured intracranial aneurysm treatment score: comparison with real-world cerebrovascular practice.
OBJECTIVE The purpose of this study was to compare the unruptured intracranial aneurysm treatment score (UIATS) recommendations with the real-world experience in a quaternary academic medical centerExpand
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Prognostic role of mitochondrial pyruvate carrier in isocitrate dehydrogenase-mutant glioma.
OBJECTIVEGliomas are one of the most common types of primary brain tumors. Recent studies have supported the importance of key genetic alterations, including isocitrate dehydrogenase (IDH) mutationsExpand
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A practical review of prognostic correlations of molecular biomarkers in glioblastoma.
Despite extensive efforts in research and therapeutics, achieving longer survival for patients with glioblastoma (GBM) remains a formidable challenge. Furthermore, because of rapid advances in theExpand
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The genetic basis of intradural spinal tumors and its impact on clinical treatment.
Genetic alterations in the cells of intradural spinal tumors can have a significant impact on the treatment options, counseling, and prognosis for patients. Although surgery is the primary therapyExpand
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