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Combined oral contraceptives in women with systemic lupus erythematosus.
BACKGROUND Oral contraceptives are rarely prescribed for women with systemic lupus erythematosus, because of concern about potential negative side effects. In this double-blind, randomized,Expand
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Systematic Review: Comparative Effectiveness of Treatments to Prevent Fractures in Men and Women with Low Bone Density or Osteoporosis
Context Sorting through the proven benefits and harms of the agents available for treating osteoporosis is difficult. Contribution This systematic review of 76 randomized trials and 24 meta-analysesExpand
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The Effect of Combined Estrogen and Progesterone Hormone Replacement Therapy on Disease Activity in Systemic Lupus Erythematosus: A Randomized Trial
Context Clinicians sometimes avoid hormone replacement therapy (HRT) in women with systemic lupus erythematosus (SLE) because they think estrogens activate the disease. Contribution In thisExpand
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Proinflammatory high-density lipoprotein as a biomarker for atherosclerosis in patients with systemic lupus erythematosus and rheumatoid arthritis.
OBJECTIVE Women with systemic lupus erythematosus (SLE) have a 7-50-fold increased risk of coronary artery disease (CAD). In the general population, oxidized low-density lipoprotein (ox-LDL)Expand
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The pathogenesis of atherosclerosis in autoimmune rheumatic diseases: roles of inflammation and dyslipidemia.
As patients with autoimmune rheumatic diseases live longer due to improved therapies and preventive measures, death and disability from atherosclerosis, particularly myocardial infarcts, areExpand
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Dysfunctional proinflammatory high-density lipoproteins confer increased risk of atherosclerosis in women with systemic lupus erythematosus.
OBJECTIVE Women with systemic lupus erythematosus (SLE) have an increased risk of atherosclerosis. Identification of at-risk patients and the etiology underlying atherosclerosis in SLE remainExpand
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The Effect of Inhibition of 5-Lipoxygenase by Zileuton in Mild-to-Moderate Asthma
Although intermittent episodic airway narrowing occurs in persons with asthma, the biochemical basis of this obstruction has not been elucidated. Nonetheless, inflammatory cells present in theExpand
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Novel nonsense gain-of-function NFKB2 mutations associated with a combined immunodeficiency phenotype.
NF-κB signaling through its NFKB1-dependent canonical and NFKB2-dependent noncanonical pathways plays distinctive roles in a diverse range of immune processes. Recently, mutations in these 2 genesExpand
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