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A multicenter double blind study
TLDR
Evaluation of symptom relief, “global efficacy,” and antacid consumption rates supported the efficacy of cimetidine compared with placebo, and there was little correlation between ulcer healing and symptom improvement. Expand
Effect of cimetidine on gastric hypersecretion and diarrhea in systemic mastocytosis.
TLDR
There was no evidence for an increase in the number of H-2 receptors during the long period of blockade or of involution of the parietal or peptic cell mass in two patients with systemic mastocytosis and histamine excess. Expand
Lymphoma simulating Crohn's colitis
SummaryA patient with lymphomatous colitis whose disease mimicked Crohn's colitis has been presented. The diagnosis was not made despite multiple endoscopic biopsies. Lymphomatous colitis may produceExpand
Cimetidine in the treatment of duodenal ulcer: A multicenter double blind study
Abstract The effect of cimetidine in duodenal ulcer disease was assessed in a double blind, controlled, prospective, multicenter clinical trial in both inpatients and outpatients. Endoscopic evidenceExpand
Cimetidine in the treatment of duodenal ulcer: a multicenter double blind study.
Abstract The effect of cimetidine in duodenal ulcer disease was assessed in a double blind, controlled, prospective, multicenter clinical trial in both inpatients and outpatients. Endoscopic evidenceExpand
Effect of Actinomycin D on Paget's Disease of Bone
Four patients with active Paget's disease were treated with the RNA inhibitor actinomycin D. Three were clinically improved after treatment; the fourth had multiple collapsed vertebrae and showed noExpand
Early clinical experience with cimetidine in duodenal ulcer patients
TLDR
Measurement of gastric secretion showed that tolerance to cimetidine had not developed after six weeks treatment, and Cimetidine appears to be a safe and effective means of controlling duodenal ulcer symptoms. Expand
Zollinger-Ellison syndrome unresponsive to cimetidine.
TLDR
Because of continuing pain and progressive bleeding from his duodenal ulcer, total gastrectomy was performed and evidence of the effect of atropine and of oral and intravenous cimetidine is presented. Expand
Changes in serum total and pancreatic amylase after administration of secretin and cholecystokinin-pancreozymin in patients with early and advanced chronic pancreatitis, and in normal subjects
TLDR
In both disease groups, the measurement of serum pancreatic amylase was at least as accurate as duodenal intubation in detecting pancreatic dysfunction, and in the group with early disease there appeared to be a clear advantage for the evocative serum test. Expand
Vagal effects on acid and pepsin secretion and serum gastrin in duodenal ulcer and controls
TLDR
Male DU but not female DU patients secreted more acid and pepsin than females under all conditions, differences that persisted in DUbut not in controls when outputs were corrected for body weight. Expand
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