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The importance of GRAS to the functional food and nutraceutical industries.
At a time when 150 million Americans spend over $20.5 billion on functional foods, nutraceuticals and dietary supplements, the Food and Drug Administration (FDA) is doing little to ensure that allExpand
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Bioactive nutrients ‐ Time for tolerable upper intake levels to address safety
Abstract There is increasing interest by consumers, researchers, and regulators into the roles that certain bioactive compounds, derived from plants and other natural sources, can play in healthExpand
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Coloring foods & beverages
food. Studies demonstrate that color predetermines our expectations of flavor and taste. Consumers perceive that yellow goes with “lemon” and pink goes with “grapefruit.” Reversing the colors changesExpand
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Safety evaluation of a natural tomato oleoresin extract derived from food-processing tomatoes.
Experimental and epidemiological studies indicate that consumption of tomato products containing high amounts of lycopene is associated with lowered cancer risk. The protective effects of lycopeneExpand
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Exploring the benefits and challenges of establishing a DRI-like process for bioactives
Bioactives can be defined as: “Constituents in foods or dietary supplements, other than those needed to meet basic human nutritional needs, which are responsible for changes in health status” (OfficeExpand
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Safety of ephedra: lessons learned.
The safe use of ephedra represents the best possible outcome of a convergence of variables, some with troubling potential outcomes. Commercially used ephedra and its products is prepared from EphedraExpand
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Dietary guidance for lutein: consideration for intake recommendations is scientifically supported
Lutein, a yellow xanthophyll carotenoid found in egg yolks and many colorful fruits and vegetables, has gained public health interest for its putative role in visual performance and reducing the riskExpand
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Toxicology and pharmacology of sodium ricinoleate.
Ricinoleic acid constitutes approximately 90% of the fatty acid content of castor oil. Castor oil is known for its purgative effects and can be used to induce labor. Both castor oil and ricinoleicExpand
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Nutrient reference value: non-communicable disease endpoints—a conference report
Nutrition is complex—and seemingly getting more complicated. Most consumers are familiar with “essential nutrients,” e.g., vitamins and minerals, and more recently protein and important amino acids.Expand
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Assessing Natural Product-Drug Interactions: An End-to-End Safety Framework.
The use of natural products (NPs), including herbal medicines and other dietary supplements, by North Americans continues to increase across all age groups. This population has access to conventionalExpand
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