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Impact of prednisone on TGF‐β1 and collagen in diaphragm muscle from mdx mice
TLDR
It is indicated that short‐term treatment of mdx mice with prednisone can attenuate the fibrotic response in diaphragm muscle, possibly by mediating the level of TGF‐β.
Strength and endurance in the therapeutic evaluation of prednisolone-treated MDX mice.
TLDR
Test results from this study support the limited therapeutic benefit observed previously in DMD patients treated with the glucocorticoid and protect mdx mice from the stressful effect of continuous running as determined by strength and muscle fiber diameter.
Regenerated mdx mouse skeletal muscle shows differential mRNA expression.
TLDR
A screen of 12,488 mRNAs in 16-wk-old mouse mdx muscle at a time when the skeletal muscle is avoiding severe dystrophic pathophysiology, despite the absence of a functional dystrophin protein suggested that transcripts whose levels differed between the mdx and human Duchenne muscular dystrophy could provide candidates for salvage pathways that maintain skeletal muscle integrity.
Cromolyn increases strength in exercised mdx mice.
TLDR
The results of this study suggest a possible use for cromolyn-like compounds in the treatment of Duchenne muscular dystrophy.
Efficacy of drug regimen exceeds electrostimulation in treatment of avian muscular dystrophy.
TLDR
Findings support the use of drug treatment as a useful nongenetic approach to the management of human muscular dystrophy where there is the potential risk of injury from exercise usage.
Enhanced sensitivity of mdx mice to intramuscular injection of compound 48/80.
TLDR
Results are consistent with the hypothesis that species-specific differences in mast cell activity, or sensitivity to mast cell products could account for the variation in pathology seen in dystrophin-deficient animals.
Abstract 208: A novel cell culture surface supports effective formation of three dimensional cancer spheroids in suspension.
TLDR
It is hypothesized that a hydrophilic polymer coated surface, Thermo Scientific Nunclon Sphera, inhibits cell attachment to the culture dish by blocking binding of the extracellular matrix (ECM) in a manner aiding in three dimensional modeling of cancer cells in vitro.
Benchmark performance of Matrix 2D-barcoded cryostorage tubes
Cryostorage tubes often hold high-value and important samples over long periods of time. Since the primary role of these tubes is to maintain samples without allowing any alterations during their
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