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Enzinger and Weiss's Soft Tissue Tumors
TLDR
The Enzinger and Weiss's soft tissue tumors are described, a large number of which consist of "hard-to-reach granuloma-like deposits". Expand
The novel marker, DOG1, is expressed ubiquitously in gastrointestinal stromal tumors irrespective of KIT or PDGFRA mutation status.
TLDR
Reactivity for DOG1 may aid in the diagnosis of GISTs, including PDGFRA mutants that fail to express KIT antigen, and lead to appropriate treatment with imatinib mesylate, an inhibitor of the KIT tyrosine kinase. Expand
Serrated Lesions of the Colorectum: Review and Recommendations From an Expert Panel
TLDR
It is recommended that all serrated lesions proximal to the sigmoid colon and allserrated lesions in the rectosigmoid >5 mm in size, be completely removed. Expand
Extragastrointestinal (Soft Tissue) Stromal Tumors: An Analysis of 48 Cases with Emphasis on Histologic Predictors of Outcome
The clinicopathologic features of 48 tumors that were histologically similar to gastrointestinal stromal tumors but occurred in the soft tissues of the abdomen were analyzed to determine theirExpand
Dedifferentiated liposarcoma: a clinicopathological analysis of 155 cases with a proposal for an expanded definition of dedifferentiation.
TLDR
The study supports the expansion of the definition of dedifferentiated liposarcoma to include tumors with low- grade dedifferentiation and also suggests that low-grade dedifferentation represents a precursor lesion of high-grade Dedifferentiation. Expand
Morphologic and Immunophenotypic Diversity in Ewing Family Tumors: A Study of 66 Genetically Confirmed Cases
TLDR
Most, but not all, EFTs can be accurately diagnosed using time-honored morphologic criteria and ancillary immunohistochemistry, however, genetic confirmation remains essential for the diagnosis of unusual morphologic variants of EFT, including “adamantinoma-like,” spindled, sclerosing, and clear cell/anaplastic variants. Expand
A critical review of the diagnosis and management of Barrett's esophagus: the AGA Chicago Workshop.
TLDR
Based on this review of BE, the opinions of workshop members on issues pertaining to screening and surveillance are at variance with published clinical guidelines. Expand
A landscape effect in tenosynovial giant-cell tumor from activation of CSF1 expression by a translocation in a minority of tumor cells.
TLDR
It is shown that CSF1 is the gene at the chromosome 1p13 breakpoint and suggested a tumor-landscaping effect with aberrant CSF 1 expression in the neoplastic cells, leading to the abnormal accumulation of nonneoplastic Cells that form a tumorous mass. Expand
A Distinctive Subset of PEComas Harbors TFE3 Gene Fusions
TLDR
A subset of lesions currently classified as PEComas harbors TFE3 gene fusions, and distinctive features of these cases include a tendency to young age, the absence of association with tuberous sclerosis, predominant alveolar architecture and epithelioid cytology, minimal immunoreactivity for muscle markers, and strong (3+) T FE3 immunore activity. Expand
Radiofrequency ablation in Barrett's esophagus with dysplasia.
TLDR
In patients with dysplastic Barrett's esophagus, radiofrequency ablation was associated with a high rate of complete eradication of both dysplasia and intestinal metaplasia, and a reduced risk of disease progression. Expand
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