• Publications
  • Influence
Identifying Specific Causes of Kidney Allograft Loss
The causes of kidney allograft loss remain unclear. Herein we investigated these causes in 1317 conventional kidney recipients. The cause of graft loss was determined by reviewing clinical andExpand
  • 591
  • 31
  • PDF
Complete Avoidance of Calcineurin Inhibitors in Renal Transplantation: A Randomized Trial Comparing Sirolimus and Tacrolimus
Calcineurin inhibitors have decreased acute rejection and improved early renal allograft survival, but their use has been implicated in the development of chronic nephrotoxicity. We performed aExpand
  • 284
  • 20
Transplant Glomerulopathy: Subclinical Incidence and Association with Alloantibody
Transplant glomerulopathy (TG) usually has been described as part of a constellation of late chronic histologic abnormalities associated with proteinuria and declining function. The current studyExpand
  • 302
  • 17
A Comparison of Plasmapheresis Versus High‐Dose IVIG Desensitization in Renal Allograft Recipients with High Levels of Donor Specific Alloantibody
Several protocols allow for the successful transplantation of sensitized renal allograft recipients, yet no one best method has emerged. The aim of the current study was to compare the efficacy ofExpand
  • 362
  • 12
Proteasome Inhibition Causes Apoptosis of Normal Human Plasma Cells Preventing Alloantibody Production
Antibody production by normal plasma cells (PCs) against human leukocyte antigens (HLA) can be a major barrier to successful transplantation. We tested four reagents with possible activity againstExpand
  • 276
  • 12
Terminal Complement Inhibition Decreases Antibody‐Mediated Rejection in Sensitized Renal Transplant Recipients
Sensitized renal transplant recipients with high levels of donor‐specific alloantibody (DSA) commonly develop antibody‐mediated rejection (AMR), which may cause acute graft loss or shorten allograftExpand
  • 449
  • 11
Histologic Findings One Year After Positive Crossmatch or ABO Blood Group Incompatible Living Donor Kidney Transplantation
Recent protocols have allowed successful positive crossmatch (+XM) and ABO incompatible (ABOI) kidney transplantation, although their long‐term outcome is not clear. To begin to assess this issue weExpand
  • 180
  • 11
Kidney Transplant Function and Histological Clearance of Virus Following Diagnosis of Polyomavirus‐Associated Nephropathy (PVAN)
Polyomavirus‐associated nephropathy (PVAN) is managed by reduced immunosuppression with or without antiviral therapy. Data from 55 patients with biopsy‐proven PVAN were analyzed for adverse outcomesExpand
  • 142
  • 10
Overcoming a Positive Crossmatch in Living‐Donor Kidney Transplantation
Many patients who have an otherwise acceptable living‐kidney donor do not undergo transplantation because of the presence of antibodies against the donor cells resulting in a positive crossmatch. InExpand
  • 247
  • 9
Accommodation in ABO‐Incompatible Kidney Allografts, a Novel Mechanism of Self‐Protection Against Antibody‐Mediated Injury
To elucidate the mechanism of self‐protection against anti‐donor blood‐group antibody known as accommodation, we studied 16 human ABO‐incompatible living‐donor kidney transplant recipients at 3 andExpand
  • 195
  • 9