Share This Author
Alzheimer's disease peptide β-amyloid interacts with fibrinogen and induces its oligomerization
- H. J. Ahn, D. Zamolodchikov, M. Cortés-Canteli, E. Norris, J. Glickman, S. Strickland
- BiologyProceedings of the National Academy of Sciences
- 22 November 2010
It is indicated that the interaction between Aβ and fibrinogen may be an important contributor to the vascular abnormalities found in AD.
A novel Aβ-fibrinogen interaction inhibitor rescues altered thrombosis and cognitive decline in Alzheimer’s disease mice
- H. J. Ahn, J. Glickman, S. Strickland
- Biology, ChemistryThe Journal of experimental medicine
- 2 June 2014
Pharmacological disruption of the interaction between fibrinogen and β-amyloid reduces vascular amyloid deposition and improves cognition in a mouse model of Alzheimer’s disease.