• Publications
  • Influence
Plant resistance towards insect herbivores: a dynamic interaction.
  • J. Gatehouse
  • Medicine, Biology
  • The New phytologist
  • 1 November 2002
Both plant defence and insect adaptation involve a metabolic cost, and in a natural system most plant-insect interactions involving herbivory reach a 'stand-off' where both host and herbivore survive but develop suboptimally. Expand
RNAi-mediated crop protection against insects.
Downregulation of the expression of specific genes through RNA interference (RNAi), has been widely used for genetic research in insects. The method has relied on the injection of double-stranded RNAExpand
Differentially regulated inhibitor-sensitive and insensitive protease genes from the phytophagous insect pest, Helicoverpa armigera, are members of complex multigene families.
It is suggested that multiple, varying protease-encoding genes are an adaptive mechanism for reducing the deleterious effects of plant protease inhibitors. Expand
Expression of the insecticidal lectin from snowdrop (Galanthus nivalis agglutinin; GNA) in transgenic wheat plants: effects on predation by the grain aphid Sitobion avenae
It is proposed that transgenic approaches using insecticidal genes such as gna in combination with integrated pest management present promising opportunities for the control of damaging wheat pests. Expand
Genome Sequence of the Pea Aphid Acyrthosiphon pisum
The genome of the pea aphid shows remarkable levels of gene duplication and equally remarkable gene absences that shed light on aspects of aphid biology, most especially its symbiosis with Buchnera.
Effects of snowdrop lectin (GNA) delivered via artificial diet and transgenic plants on the development of tomato moth (Lacanobia oleracea) larvae in laboratory and glasshouse trials.
The assays show that the insecticidal effects of GNA can be observed both in vitro when fed in artificial diet and in planta, and can be demonstrated in the glasshouse as well as under growth cabinet conditions. Expand
Immunohistochemical and developmental studies to elucidate the mechanism of action of the snowdrop lectin on the rice brown planthopper, Nilaparvata lugens (Stal).
Observations suggest that GNA is able to cross the midgut epithelial barrier, and pass into the insect's circulatory system, resulting in a systemic toxic effect. Expand
Biotechnological Prospects for Engineering Insect-Resistant Plants1[C]
Insect-resistant crops have been one of the major successes of applying plant genetic engineering technology to agriculture; cotton and maize resistant to both lepidopteran and coleopteran larvae (rootworms) have been a major success. Expand
Expression of snowdrop lectin (GNA) in transgenic rice plants confers resistance to rice brown planthopper.
Insect bioassays and feeding studies showed that GNA expressed in the transgenic rice plants decreased survival and overall fecundity of the insects, retarded insect development, and had a deterrent effect on BPH feeding. Expand
Snowdrop lectin inhibits development and decreases fecundity of the Glasshouse Potato Aphid (Aulacorthum solani) when administered in vitro and via transgenic plants both in laboratory and glasshouse
The experiments demonstrate that the insecticidal effects of GNA observed in artificial diets can be reproduced in planta, both under laboratory bioassay conditions and in the glasshouse. Expand