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Experimental nasopharyngitis and pneumonia caused by Chlamydia trachomatis in infant baboons: histopathologic comparison with a case in a human infant.
TLDR
Three infant male baboons were inoculated with a strain of CHLAMYDIA TRACHOMATIS isolated from a human infant with pneumonia and seroconverted, appearing to be useful animal models for C. trachomatis nasopharyngitis and pneumonia.
Salpingitis in mice induced by human strains of Chlamydia trachomatis.
TLDR
There was evidence that the susceptibility of different strains of mice to chlamydial salpingitis varied and the changes in C3H and CBA strains were longer lasting than those in TO mice, suggesting that a possible genetic predisposition in the human situation should not be ignored.
Infertility in mice infected genitally with a human strain of Chlamydia trachomatis.
TLDR
A difference in the susceptibility of mouse strains suggests that a genetic predisposition should be considered for man, and could explain the high incidence of ectopic pregnancies in women after chlamydial infection.
Tuberculosis due to Mycobacterium bovis in pet cats associated with feeding a commercial raw food diet
TLDR
An outbreak of tuberculous disease commencing with six young cats, living exclusively indoors in five different households across England, being presented to separate veterinarians across the UK with a variety of clinical signs provides compelling, if circumstantial, evidence of an association between the commercial raw diet of these cats and their M bovis infections.
Failure of Chlamydia trachomatis to pass transplacentally to fetuses of TO mice infected during pregnancy.
TLDR
These experiments show that C. trachomatis did not cross the placenta and that the pregnancy outcome in these mice was not affected, and chlamydiae were not recovered from fetal tissue, even when there was heavy placental colonisation.
COVID-19 Status, Symptom Burden, and Characteristics of Dialysis Patients Residing in Areas of Community Transmission: Research Letter
TLDR
In this study of hemodialysis patients residing in areas with community spread who otherwise did not meet symptom criteria for being “at-risk,” no individual who tested positive for SARS-CoV-2 was identified and future studies are needed to examine the utility of routine testing for COVID-19 in areas of higher disease prevalence.
BI02: Melanized (dematiaceous) fungal infections simulating skin cancer in African organ transplant recipients
TLDR
The first case of using IV cidofovir in an immunocompromised, HIV-negative woman with severe and recalcitrant MC, and two African OTRs with deep fungal infections caused by dematiaceous (melanized, pigmented or black) fungi, who both presented with suspected skin malignancies are reported.
BI01: Intravenous cidofovir treatment of severe giant molluscum contagiosum presenting with myiasis
TLDR
The first case of using IV cidofovir in an immunocompromised, HIV-negative woman with severe and recalcitrant MC, and two African OTRs with deep fungal infections caused by dematiaceous (melanized, pigmented or black) fungi, who both presented with suspected skin malignancies are reported.