Intention‐to‐treat analysis of surgical treatment for early hepatocellular carcinoma: Resection versus transplantation
In conclusion, a proper selection of candidates for resection promotes better results than transplantation, in which the results are significantly hampered by the growing incidence of drop‐outs because of the increasing waiting time.
Integrative molecular analysis of intrahepatic cholangiocarcinoma reveals 2 classes that have different outcomes.
- D. Sia, Y. Hoshida, J. Llovet
- Medicine, BiologyGastroenterology
- 1 April 2013
An integrative genomic analysis of ICC samples from a large series of patients identified a gene expression signature that was associated with reduced survival times of patients with ICC and was enriched in the proliferation class.
Surgical resection of hepatocellular carcinoma in cirrhotic patients: prognostic value of preoperative portal pressure.
- J. Bruix, A. Castells, J. Rodés
- MedicineGastroenterology
- 1 October 1996
The Barcelona approach: Diagnosis, staging, and treatment of hepatocellular carcinoma
The present manuscript depicts the Barcelona‐Clínic Liver Cancer Group diagnostic and treatment strategy, based on the analysis of several cohort and randomized controlled studies that have allowed the continuous refinement of treatment indication and application.
Liver Transplant Using Donors After Unexpected Cardiac Death: Novel Preservation Protocol and Acceptance Criteria
- C. Fondevila, A. Hessheimer, J. García‐Valdecasas
- Medicine, EngineeringAmerican Journal of Transplantation
- 1 July 2007
Though considered marginal, unexpected DCD can represent an important source of viable livers for transplant if strict acceptance criteria are employed and they are maintained with NECMO prior to recovery.
Applicability and Results of Maastricht Type 2 Donation After Cardiac Death Liver Transplantation
- C. Fondevila, A. Hessheimer, J. García‐Valdecasas
- MedicineAmerican Journal of Transplantation
- 1 January 2012
The applicability of type 2 DCD liver transplant was <10%; however, with better preservation technology and expanded transplant criteria, this figure may be able to improve this figure significantly.
Massive parallel sequencing uncovers actionable FGFR2-PPHLN1 fusion and ARAF mutations in intrahepatic cholangiocarcinoma.
It is demonstrated that the chromosomal translocation t(10;12)(q26;q12) leading toFGFR2-PPHLN1 fusion possesses transforming and oncogenic activity, which is successfully inhibited by a selective FGFR2 inhibitor in vitro.
Hepatitis C recurrence is more severe after living donor compared to cadaveric liver transplantation
- M. García-Retortillo, X. Forns, A. Rimola
- MedicineHepatology
- 1 September 2004
The results were based on a single‐center experience and should be considered in the decision‐making process of transplant programs, since severe HCV recurrence may ultimately compromise graft and patient survival.
Bacterial translocation of enteric organisms in patients with cirrhosis.
- I. Cirera, T. M. Bauer, J. Rodés
- Medicine, BiologyJournal of Hepatology
- 2001
Treatment of small hepatocellular carcinoma in cirrhotic patients: A cohort study comparing surgical resection and percutaneous ethanol injection
- A. Castells, J. Bruix, J. Rodés
- MedicineHepatology
- 1 November 1993
It is confirmed that ethanol injection is a useful treatment for patients with solitary small hepatocellular carcinomas and suggest that surgical resection and liver transplantation may achieve better results only after strict candidate selection to reduce mortality and tumor recurrence during follow‐up.
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