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Optical coherence tomography
A technique called optical coherence tomography (OCT) has been developed for noninvasive cross-sectional imaging in biological systems. OCT uses low-coherence interferometry to produce a… Expand
Split-spectrum amplitude-decorrelation angiography with optical coherence tomography
Amplitude decorrelation measurement is sensitive to transverse flow and immune to phase noise in comparison to Doppler and other phase-based approaches. However, the high axial resolution of OCT… Expand
Ultrahigh-resolution, high-speed, Fourier domain optical coherence tomography and methods for dispersion compensation.
- M. Wojtkowski, V. Srinivasan, T. Ko, J. Fujimoto, A. Kowalczyk, J. Duker
- Physics, Medicine
- Optics express
- 31 May 2004
Ultrahigh-resolution optical coherence tomography uses broadband light sources to achieve axial image resolutions on the few micron scale. Fourier domain detection methods enable more than an order… Expand
State-of-the-art retinal optical coherence tomography
- W. Drexler, J. Fujimoto
- Computer Science, Medicine
- Progress in Retinal and Eye Research
- 31 January 2008
OCT functions as a type of optical biopsy, providing information on retinal pathology in situ and in real time, with resolutions approaching that of excisional biopsy and histopathology. Expand
Optical coherence tomography of the human retina.
- M. Hee, J. Izatt, +5 authors J. Fujimoto
- Medicine, Materials Science
- Archives of ophthalmology
- 1 March 1995
OBJECTIVE To demonstrate optical coherence tomography for high-resolution, noninvasive imaging of the human retina. Optical coherence tomography is a new imaging technique analogous to ultrasound B… Expand
Polarization-sensitive low-coherence reflectometer for birefringence characterization and ranging
We present a polarization-sensitive optical coherence-domain reflectometer capable of characterizing the phase retardation between orthogonal linear polarization modes at each reflection point in a… Expand
Topography of diabetic macular edema with optical coherence tomography.
OBJECTIVE This study aimed to develop a protocol to screen and monitor patients with diabetic macular thickening using optical coherence tomography (OCT), a technique for high-resolution… Expand
Optical coherence tomography using a frequency-tunable optical source.
We have developed a simple, wide-optical-bandwidth, high-resolution system for performing rapid optical frequency domain reflectometry measurements and applied it to multidimensional tomographic… Expand
Optical coherence tomography for ultrahigh resolution in vivo imaging
- J. Fujimoto
- Materials Science, Medicine
- Nature Biotechnology
- 1 November 2003
Optical coherence tomography (OCT) is an emerging biomedical optical imaging technique that performs high-resolution, cross-sectional tomographic imaging of microstructure in biological systems. OCT… Expand
Redefining lamellar holes and the vitreomacular interface: an ultrahigh-resolution optical coherence tomography study.
OBJECTIVES To define optical coherence tomographic (OCT) criteria for the diagnosis of a lamellar macular hole, and to increase understanding of lamellar hole pathogenesis by examining fine anatomic… Expand