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Orofacial granulomatosis: review on aetiology and pathogenesis.
- W. Tilakaratne, J. Freysdottir, F. Fortune
- MedicineJournal of oral pathology & medicine : official…
- 23 July 2007
The term idiopathic OFG is proposed as a better term for those cases restricted to oral region without any identifiable known granulomatous disease and the diagnosis should not be changed until the patient develops systemic manifestations of a specific granulOMatous condition.
Expression of cytokines, chemokines, and chemokine receptors in oral ulcers of patients with Behcet's disease (BD) and recurrent aphthous stomatitis is Th1‐associated, although Th2‐association is…
- A. Dalghous, J. Freysdottir, F. Fortune
- Medicine, BiologyScandinavian journal of rheumatology
- 1 January 2006
This is the first study that shows the presence of pro‐inflammatory cytokines, as well as Th1‐associated chemokine receptors, in the oral ulcers of BD patients, aswell as RAS patients, at a protein level.
Exopolysaccharides from Cyanobacterium aponinum from the Blue Lagoon in Iceland increase IL-10 secretion by human dendritic cells and their ability to reduce the IL-17+RORγt+/IL-10+FoxP3+ ratio in…
The influence of partial or total thymectomy during open heart surgery in infants on the immune function later in life
- J. H. Eysteinsdóttir, J. Freysdottir, H. Ogmundsdottir
- Medicine, BiologyClinical and experimental immunology
- 1 May 2004
Results indicate a shift to extrathymic T cell maturation, which is less efficient for CD4+ helper cells than for CD8+ cytotoxic cells, which may indicate enhanced innate immunity when the acquired immunity is defective.
Evidence for extrathymic T cell maturation after thymectomy in infancy
- H. Torfadóttir, J. Freysdottir, I. Skaftadottir, Á. Haraldsson, G. Sigfússon, H. Ogmundsdottir
- Biology, MedicineClinical and experimental immunology
- 1 September 2006
The phenotypic characteristics of T lymphocytes of children who have lost their thymus in infancy are indicative of extrathymic maturation and T regulatory cells appear to be less affected than other subsets by the general reduction in T cell numbers.
Expression of adhesion and activation molecules in human buccal epithelial cell lines and normal human buccal epithelium in situ.
- I. Farmer, J. Freysdottir, A. Dalghous, F. Fortune
- Biology, MedicineJournal of oral pathology & medicine : official…
- 1 February 2001
These buccal squamous epithelial cell lines provide a good tool for analysing interactions between epithelium and T cells in vitro, and when the SVpgC2a cell line was treated with T-cell derived cytokines, upregulation of CD40 expression was observed.
In vitro and in vivo immunomodulating effects of traditionally-prepared extract and purified compounds from Cetraria islandica
- J. Freysdottir, S. Ómarsdóttir, K. Ingolfsdottir, A. Víkingsson, E. S. Olafsdottir
- BiologyProceedings of the Nutrition Society
- 1 May 2008
Results suggest that the aqueous extract of C. islandica has an anti-inflammatory effect, possibly by changing the cytokine secretion bias from IL-12 towards IL-10, and not isolichenan or the secondary metabolites.
Vβ Usage and T Regulatory Cells in Children Following Partial or Total Thymectomy after Open Heart Surgery in Infancy
- J. H. Eysteinsdóttir, J. Freysdottir, I. Skaftadottir, H. Helgason, Á. Haraldsson, H. Ogmundsdottir
- Biology, MedicineScandinavian journal of immunology
- 1 February 2009
The data provide evidence that cardiothoracic surgery in infants and total or partial thymectomy alters Vβ usage, suggesting more limited selection in such children than in the control group.
6-Bromoindole Derivatives from the Icelandic Marine Sponge Geodia barretti: Isolation and Anti-Inflammatory Activity
Results indicate that 2 and 3 may be useful for the treatment of inflammation, mainly of the Th1 type.