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Dendrimers and other dendritic polymers
TLDR
The author reveals some unique Features of Dendrimers based upon Self--assembly and Host--Guest Properties that have attracted attention in the literature on Dendritic Polymers and their applications in Nanobiological Devices.
Designing dendrimers for biological applications
TLDR
Advances in understanding of the role of molecular weight and architecture on the in vivo behavior of dendrimers, together with recent progress in the design of biodegradable chemistries, has enabled the application of these branched polymers as anti-viral drugs, tissue repair scaffolds, targeted carriers of chemotherapeutics and optical oxygen sensors.
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Acetal-derivatized dextran: an acid-responsive biodegradable material for therapeutic applications.
TLDR
Owing to its ease of preparation, processability, pH-sensitivity, and biocompatibility, this type of modified dextran should find use in numerous drug delivery applications.
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Preparation of polymers with controlled molecular architecture. A new convergent approach to dendritic macromolecules
The novel convergent growth approach to topological macromolecules based on dendritic fragments is described. The polyether dendritic fragments are prepared by starting from what will become the…
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Continuous rods of macroporous polymer as high-performance liquid chromatography separation media
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Acetalated dextran is a chemically and biologically tunable material for particulate immunotherapy
Materials that combine facile synthesis, simple tuning of degradation rate, processability, and biocompatibility are in high demand for use in biomedical applications. We report on acetalated…
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Polymer-fullerene composite solar cells.
TLDR
Polymer-based organic photovoltaic systems hold the promise for a cost-effective, lightweight solar energy conversion platform, which could benefit from simple solution processing of the active layer.
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A single dose of doxorubicin-functionalized bow-tie dendrimer cures mice bearing C-26 colon carcinomas
TLDR
The remarkable antitumor activity of dendrimer–DOX results from the ability of the d endrimer to favorably modulate the pharmacokinetics of attached DOX.
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One-step synthesis of hyperbranched dendritic polyesters
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In vivo targeting of dendritic cells for activation of cellular immunity using vaccine carriers based on pH-responsive microparticles.
TLDR
Antigens were encapsulated in acid-degradable polymeric particle carriers to cascade cytotoxic T lymphocyte activation to target dendritic cells, and the most potent antigen-presenting cells, the particle carriers, were further conjugated with monoclonal antibodies.
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