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A simple method for the isolation and purification of total lipides from animal tissues.
TLDR
A simplified version of the method for the preparation and purification of brain lipides has the advantage of being simpler, of being applicable to any scale desired, of substantially decreasing the losses of lipides incidental to the washing process, and of yielding a washed extract which can be taken to dryness without foaming and without splitting of the proteolipides. Expand
Preparation of lipide extracts from brain tissue.
TLDR
A simple method is described for the preparation of extracts of total pure lipides from brain tissue by homogenizing the tissue with a chloroform-methanol mixture and washing free of non-lipide contaminants. Expand
THE ISOLATION FROM BRAIN TISSUE OF A TRYPSIN‐RESISTANT PROTEIN FRACTION CONTAINING COMBINED INOSITOL, AND ITS RELATION TO NEUROKERATIN *
TLDR
Results obtained in this laboratory in the course of work on the nature of neurokeratin have established the presence in brain tissue of a second form of combined inositol, namely, that of a phosphoinositide combined to protein. Expand
Brain diphosphoninositide, a new phosphatide having inositol metadiphosphate as a constituent.
  • J. Folch
  • Medicine, Chemistry
  • The Journal of biological chemistry
  • 1 February 1949
TLDR
It has been shown that diphosphoinositide has inositol metadiphosphate’ as a constituent, and detailed proof of this statement is provided and some other observations are reported which establish in part the chemical structure of diph phosphate. Expand
Proteolipides, a new type of tissue lipoproteins; their isolation from brain.
  • J. Folch, M. Lees
  • Biology, Medicine
  • The Journal of biological chemistry
  • 1 August 1951
Some studies on the properties of proteolipids.
Isolation of brain strandin, a new type of large molecule tissue component.
TLDR
The isolation from brain tissue of a substance to which the name of strandin has been given for descriptive purposes is reported, which has the property of forming long strands that show perfect orientation under polarized light. Expand
THE EFFECT OF pH AND SALT CONCENTRATION ON AQUEOUS EXTRACTION OF BRAIN PROTEINS AND LIPOPROTEINS *
TLDR
A survey of the effect of p H and ionic strength on the amount of material extracted in aqueous solution was carried out and it was found that these mixtures can be separated by the use of a relatively high centrifugal force, and waterclear extracts can be thus obtained. Expand
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