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Eugenol Causes Melanoma Growth Suppression through Inhibition of E2F1 Transcriptional Activity*
Metastatic malignant melanoma is an extremely aggressive cancer, with no currently viable therapy. 4-Allyl-2-methoxyphenol (eugenol) was tested for its ability to inhibit proliferation of melanomaExpand
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Vulvar Clear Cells of Toker: Precursors of Extramammary Paget's Disease
Clear cells of Toker are intraepithelial cells with clear to pale staining cytoplasm and bland cytologic features found with H&E staining in approximately 10% of normal nipples. Toker cells have beenExpand
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Background. Deposition of calcium in skin is currently categorized into a group of disorders referred to as calcinosis cutis. Divisions between types and subtypes within this confusing classificationExpand
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Cutaneous involvement of multiple myeloma and extramedullary plasmacytoma.
We recently performed a retrospective clinicopathologic study of five patients with cutaneous involvement of multiple myeloma or extramedullary plasmacytoma. Cutaneous nodules without extension fromExpand
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Gastrointestinal Melanoma or Clear Cell Sarcoma? Molecular Evaluation of 7 Cases Previously Diagnosed as Malignant Melanoma
Clear cell sarcoma (CCS) is a rare tumor classically associated with the tendons and aponeuroses of distal extremities of young adults. CCS and malignant melanoma (MM) share immunohistochemicalExpand
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Completely regressed primary cutaneous malignant melanoma with nodal and/or visceral metastases: a report of 5 cases and assessment of the literature and diagnostic criteria.
BACKGROUND Partial regression of primary cutaneous malignant melanoma is not uncommon and may predict a higher likelihood of metastasis and decreased survival. Complete histologic regression of aExpand
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The histologic diagnosis of intraepithelial Pagetoid neoplasms.
Abstract The histologic differential diagnosis of entities characterized by large, pale-staining cells scattered throughout the epidermis most commonly includes Paget's disease (mammary andExpand
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A Mediator of Rho-dependent Invasion Moonlights as a Methionine Salvage Enzyme*
RhoA controls changes in cell morphology and invasion associated with cancer phenotypes. Cell lines derived from melanoma tumors at varying stages revealed that RhoA is selectively activated in cellsExpand
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Basaloid follicular hamartoma: a cautionary tale and review of the literature.
Basaloid follicular hamartoma (BFH), also referred to as benign follicular hamartoma, is a rare cutaneous follicular neoplasm that presents with small skin-colored papules on the face, scalp, and,Expand
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Papillary mesenchymal bodies: a histologic finding useful in differentiating trichoepitheliomas from basal cell carcinomas.
To distinguish a basal cell carcinoma (BCC) from a trichoepithelioma can be difficult even for an experienced dermatopathologist. Previously reported differentiating histologic features are relativeExpand
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