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Countrywide Spread of CTX-M-3 Extended-Spectrum β-Lactamase-Producing Microorganisms of the Family Enterobacteriaceae in Poland
TLDR
Analysis of clinical isolates of the family Enterobacteriaceae revealed a very high degree of diversity in β-lactam resistance levels and patterns, which was attributed to several factors, such as the production of other β- lactamases including additional ESBLs, possible quantitative variations in CTX-M-3 expression, segregation of AmpC derepressed mutants, and permeability alterations. Expand
Ceftazidime-hydrolysing CTX-M-15 extended-spectrum beta-lactamase (ESBL) in Poland.
TLDR
Three cefotaxime- and ceftazidime-resistant Enterobacteriaceae isolates recovered during 1998-2000 in two Polish hospitals were found to produce CTX-M-15, which indicated the independent selection of the ESBL gene in the two countries. Expand
Molecular Survey of β-Lactamases Conferring Resistance to Newer β-Lactams in Enterobacteriaceae Isolates from Polish Hospitals
TLDR
The survey documented both specific and more global characteristics of the epidemiology of the β-lactamase-mediated resistance in enterobacteria from Polish hospitals and demonstrated that the ESBL frequency has reached an alarming level. Expand
Ceftazidime-hydrolysing CTX-M-15 extended-spectrum β-lactamase (ESBL) in Poland
TLDR
Three cefotaxime- and ceftazidime-resistant Enterobacteriaceae isolates recovered during 1998-2000 in two Polish hospitals were found to produce CTX-M-15, which indicated the independent selection of the ESBL gene in the two countries. Expand
MLST reveals potentially high-risk international clones of Enterobacter cloacae.
TLDR
The results suggest that, like Escherichia coli and Klebsiella pneumoniae, E. cloacae harbours clonal lineages of increased epidemic potential that may be associated with resistance spread. Expand
Characteristics of Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis Isolated from the Nasopharynges of Asymptomatic Children and Molecular Analysis of S. pneumoniae and H.
TLDR
Nasopharyngeal carriage of Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis in 226 children in different settings during two seasons was studied; long-term colonization by a single strain was rare. Expand
NDM-producing Enterobacteriaceae in Poland, 2012-14: inter-regional outbreak of Klebsiella pneumoniae ST11 and sporadic cases.
TLDR
The largest NDM outbreak in a non-endemic country has been observed, being an alarming phenomenon in resistance epidemiology in Poland. Expand
Emergence of Klebsiella pneumoniae ST258 with KPC-2 in Poland
TLDR
Strains with KPCs spread rapidly and cause outbreaks; in hospitals on the east coast of the United States and in Israel, they have already become endemic and are likely to become endemic. Expand
Molecular Epidemiology of Acquired-Metallo-β-Lactamase-Producing Bacteria in Poland
TLDR
The occurrence of the integron variants correlated well with the geographic distribution of the MBL-producing organisms, and this suggested that their emergence in particular parts of the country had been likely due to a number of independent events. Expand
A Novel Complex Mutant β-Lactamase, TEM-68, Identified in a Klebsiella pneumoniae Isolate from an Outbreak of Extended-Spectrum β-Lactamase-Producing Klebsiellae
TLDR
TEM-68 was shown to be a novel complex mutant TEM β-lactamase (CMT-2) which combines strong ESBL activity with relatively weak IR activity and, when expressed in K. pneumoniae, is able to confer high-level resistance to a wide variety of β- lactams, including inhibitor combinations. Expand
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