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Antioxidant, Anti-Inflammatory, and Analgesic Activities of Agrimonia eupatoria L. Infusion
TLDR
Both AeI and mainly AePF (Ae polyphenolic fraction) showed a significant antiradical activity against all tested radicals in vitro and in vivo, and decreased NO levels in vitro, AePF being more active than AeI.
Ibuprofen Nanoparticles for Oral Delivery: Proof of Concept
Background: Using nanoparticles to improve non-steroidal anti-inflammatory drugs therapeutic profile is an interesting approach, especially concerning their gastric toxicity. Objective: The aim of
Enzymatic modification of plasma low density lipoproteins in rabbits: a potential treatment for hypercholesterolemia.
TLDR
Modification of blood lipoproteins of hypercholesterolemic rabbits was performed by using an extracorporeal circuit containing immobilized phospholipase A2, and this technique offers a potential approach for lowering serum cholesterol and LDL levels.
Evaluation of Anti-inflammatory and Analgesic Activities of Cymbopogon citratus In vivo-Polyphenols Contribution
TLDR
This study demonstrates that C. citratus 1 infusion compounds are able to reduce inflammation and peripheral pain in vivo, with polyphenols showing a significant contribution for these activities.
Influence of chemistry in immobilization of cobra venom phospholipase A2: implications as to mechanism.
TLDR
The results suggest that the enzyme activity lost upon immobilization is a result of the inherent chemical modification of the enzyme and that enzyme oligomerization and interfacial recognition are not cause-effect phenomena.
A study on the functional subunits of phospholipases A2 by enzyme immobilization.
TLDR
The results indicated that pig pancreatic and Naja naja phospholipases A2 are active as monomers, with the dimeric form as the fully active one.
Effect of drug properties on the release from CAP microspheres prepared by a solvent evaporation method.
TLDR
Drugs with different water-solubility and molecular weights were microencapsulated in cellulose acetate phthalate, using an emulsion-solvent evaporation technique with a continuous oil-phase, and the capacity of the microspheres to retain the drugs was evaluated by in vitro release studies in acidic medium.
Carbodiimide modification enhances activity of pig pancreatic phospholipase A2.
TLDR
The modified pig enzyme showed pre-micellar activation on monomeric diheptanoyl-lecithin, and either reduced or increased activities on mixed micelles of bile salt with egg phosphatidylcholine, depending on the composition of the micells.
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