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Laminar differences in the spatiotemporal structure of simple cell receptive fields in cat area 17.
Previous studies of cat visual cortex have shown that the spatiotemporal (S-T) structure of simple cell receptive fields correlates with direction selectivity. However, great heterogeneity exists in… Expand
Hebbian learning and the development of direction selectivity: the role of geniculate response timings
Zero-sum Hebbian learning rules that reinforce well correlated inputs have been used by others to model the competitive self-organization of afferents from the lateral geniculate nucleus to produce… Expand
Strobe rearing prevents the convergence of inputs with different response timings onto area 17 simple cells.
Strobe rearing prevents the convergence of inputs with different response timings onto area 17 simple cells. J. Neurophysiol. 80: 3005-3020, 1998. The preceding paper showed that the loss of… Expand
Development of Response Timing and Direction Selectivity in Cat Visual Thalamus and Cortex
Single-unit recordings were made in the dorsal lateral geniculate nucleus (LGN) and visual cortex of kittens that were 4–13 weeks of age. Responses to visual stimuli were analyzed to determine the… Expand
BioSPICE: a computational infrastructure for integrative biology.
Modeling the effects of a Staphylococcal Enterotoxin B (SEB) on the apoptosis pathway
BackgroundThe lack of detailed understanding of the mechanism of action of many biowarfare agents poses an immediate challenge to biodefense efforts. Many potential bioweapons have been shown to… Expand
Pharmacokinetics and cytotoxicity of RSU-1069 in subcutaneous 9L tumours under oxic and hypoxic conditions.
The acute toxicity, pharmacokinetics and hypoxic cytotoxicity of RSU-1069 were investigated using the subcutaneous (sc) rat 9L tumour model. The pharmacokinetics were studied after i.p. injection of… Expand
Biocompution: An emerging discipline at the intersection of the computational and biological sciences
Research at the intersection of the biological and computational sciences holds the potential to enable a number of important advances for both communities. Expand
AN EMERGING DISCIPLINE AT THE INTERSECTION OF THE COMPUTATIONAL AND BIOLOGICAL SCIENCES
Research at the intersection of th e biological and compu tational sciences holds the pot ential to enable a number of importan t advances for both communities. Expand