Cell differentiation by mechanical stress
It is demonstrated that mechanical stimulation in vitro, without ligament‐selective exogenous growth and differentiation factors, induces the differentiation of mesenchymal progenitor cells from the bone marrow into a ligament cell lineage in preference to alternative paths.
Engineered autologous cartilage tissue for nasal reconstruction after tumour resection: an observational first-in-human trial
Angiogenesis in tissue engineering: breathing life into constructed tissue substitutes.
Future directions of research should focus on the creation of microvascular networks within 3D tissue constructs in vitro before implantation or by co-stimulation of angiogenesis and parenchymal cell proliferation to engineer the vascularized tissue substitute in situ.
Identification of markers to characterize and sort human articular chondrocytes with enhanced in vitro chondrogenic capacity.
OBJECTIVE To identify markers associated with the chondrogenic capacity of expanded human articular chondrocytes and to use these markers for sorting of more highly chondrogenic subpopulations. …
Cell yield, proliferation, and postexpansion differentiation capacity of human ear, nasal, and rib chondrocytes.
- A. Tay, J. Farhadi, R. Suetterlin, G. Pierer, M. Heberer, I. Martin
- Medicine, BiologyTissue engineering
- 25 August 2004
Ear and nasal chondrocytes, if expanded with TFP, display superior postexpansion chondrogenic potential and may be a preferred cell source for cartilage tissue engineering.
Reconstruction of the nipple-areola complex: an update.
Three‐Dimensional Perfusion Culture of Human Adipose Tissue‐Derived Endothelial and Osteoblastic Progenitors Generates Osteogenic Constructs with Intrinsic Vascularization Capacity
Direct perfusion of human adipose‐derived cells through ceramic scaffolds establishes a 3D culture system for osteoprogenitor and endothelial cells and generates osteogenic‐vasculogenic constructs.
An exploration of patient decision-making for autologous breast reconstructive surgery following a mastectomy.
Engineered cartilage generated by nasal chondrocytes is responsive to physical forces resembling joint loading.
Human ECN is responsive to physical forces resembling joint loading and can up-regulate molecules typically involved in joint lubrication, and should prompt future in vivo studies exploring the possibility of using nasal chondrocytes as a cell source for articular cartilage repair.