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Lactic acidosis in critical illness
TLDR
The severity of lactic acidosis in critically ill patients correlates with overall oxygen debt and survival, and lactate determinations may be useful as an ongoing monitor of perfusion as resuscitation proceeds. Expand
Misplaced endotracheal tubes by paramedics in an urban emergency medical services system.
TLDR
The incidence of out-of-hospital, unrecognized, misplaced endotracheal tubes in this community is excessively high and may be reflective of the incidence occurring in other communities. Expand
Serum levels of ubiquitin C-terminal hydrolase distinguish mild traumatic brain injury from trauma controls and are elevated in mild and moderate traumatic brain injury patients with intracranial
TLDR
UCH-L1 is detectable in serum within an hour of injury and is associated with measures of injury severity including the GCS score, CT lesions, and NSI and further study is required to validate these findings before clinical application. Expand
Difference in acid-base state between venous and arterial blood during cardiopulmonary resuscitation.
TLDR
Mixed venous blood most accurately reflects the acid-base state during cardiopulmonary resuscitation, especially the rapid increase in PCO2, and thus arterial blood gases may fail as appropriate guides for acid- base management in this emergency. Expand
The effectiveness of out-of-hospital use of continuous end-tidal carbon dioxide monitoring on the rate of unrecognized misplaced intubation within a regional emergency medical services system.
TLDR
No unrecognized misplaced intubations were found in patients for whom paramedics used continuous ETCO2 monitoring, and failure to use continuous ETCO2 monitoring was associated with a 23% unrecognized misguided intubation rate. Expand
End-tidal carbon dioxide concentration during cardiopulmonary resuscitation.
TLDR
It is proposed that measurement of the end-tidal carbon dioxide concentration may be a practical, non-invasive method for monitoring blood flow generated by precordial compression during cardiopulmonary resuscitation and an almost immediate indicator of successful resuscitation. Expand
GFAP out-performs S100β in detecting traumatic intracranial lesions on computed tomography in trauma patients with mild traumatic brain injury and those with extracranial lesions.
TLDR
In a general trauma population, GFAP out-performed S100β in detecting intracranial CT lesions, particularly in the setting of extracranial fractures. Expand
Elevated levels of serum glial fibrillary acidic protein breakdown products in mild and moderate traumatic brain injury are associated with intracranial lesions and neurosurgical intervention.
TLDR
GFAP-BDP is detectable in serum within an hour of injury and is associated with measures of injury severity, including the GCS score, CT lesions, and neurosurgical intervention. Expand
Fluid resuscitation in circulatory shock: a comparison of the cardiorespiratory effects of albumin, hetastarch, and saline solutions in patients with hypovolemic and septic shock.
TLDR
It is concluded that 6% H performs as well as 5% A as a resuscitative fluid and that resuscitation with either of these colloids is associated with a lower incidence of pulmonary edema than is resuscitations with 0.9% S. Expand
The relationship between oxygen delivery and consumption during fluid resuscitation of hypovolemic and septic shock.
TLDR
It is concluded that increasing DO2 by fluid resuscitation increases VO2 during both hypovolemic and septic shock, and there was no significant difference in either the increase in DO2 or VO2 between the septicshock and hypovolesmic shock patients. Expand
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