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TESTING FOR GENETIC EVIDENCE OF POPULATION EXPANSION AND CONTRACTION: AN EMPIRICAL ANALYSIS OF MICROSATELLITE DNA VARIATION USING A HIERARCHICAL BAYESIAN MODEL
- J. F. Storz, M. Beaumont
- Environmental ScienceEvolution; international journal of organic…
- 1 January 2002
Alternative hypotheses about historical patterns of demographic expansion and contraction in Cynopterus sphinx and C. brachyotis are tested using a hierarchical Bayesian model based on Markov chain Monte Carlo simulations to estimate the posterior distribution of genealogical and demographic parameters.
Comparative genomics reveals insights into avian genome evolution and adaptation
This work explored bird macroevolution using full genomes from 48 avian species representing all major extant clades to reveal that pan-avian genomic diversity covaries with adaptations to different lifestyles and convergent evolution of traits.
INVITED REVIEW: Using genome scans of DNA polymorphism to infer adaptive population divergence
- J. F. Storz
- BiologyMolecular ecology
- 14 January 2005
The question of whether diversifying selection on polygenic traits can be expected to produce predictable patterns of allelic variation at the underlying quantitative trait loci (QTL) is addressed and whether the locus‐specific effects of selection can be reliably detected against the genome‐wide backdrop of stochastic variability is addressed.
Genetic Consequences of Mammalian Social Structure
- J. F. Storz
- 20 May 1999
It appears that social mammals generally are characterized by a dynamic non-equilibrium mode of population structure in which local demes are characterized simultaneously by small variance effective sizes and large inbreeding effective sizes.
Phenotypic plasticity and genetic adaptation to high-altitude hypoxia in vertebrates
- J. F. Storz, G. Scott, Z. Cheviron
- Biology, Environmental ScienceJournal of Experimental Biology
- 15 December 2010
Insights into the acclimatization response of lowland animals to high-altitude hypoxia can provide a basis for predicting how altitudinal range limits might shift in response to climate change.
Causes of molecular convergence and parallelism in protein evolution
- J. F. Storz
- BiologyNature Reviews Genetics
- 1 April 2016
Key finding is that the fitness effects of amino acid mutations are often conditional on genetic background, which reduces the probability of convergence and parallelism.
Clinal variation in body size and sexual dimorphism in an Indian fruit bat, Cynopterus sphinx (Chiroptera: Pteropodidae)
This study represents one of the first conclusively documented examples of Bergmann's Rule in a tropical mammal and confirms that latitudinal clines in body size are not exclusively restricted to temperate zone homeotherms.
Social structure of a polygynous tent-making bat, Cynopterus sphinx (Megachiroptera)
The social structure of an Old World tent-making bat Cynopterus sphinx, was investigated in western India to infer the form of the mating system, compositional stability of social groups and mode of new social group formation.
The Molecular Basis of High-Altitude Adaptation in Deer Mice
A population genetic analysis of a two-locus α-globin polymorphism that underlies physiological adaptation to high-altitude hypoxia in natural populations of deer mice, Peromyscus maniculatus, demonstrates that functionally distinct protein alleles are maintained as a long-term balanced polymorphism and that adaptive modifications of hemoglobin function are produced by the independent or joint effects of five amino acid mutations that modulate oxygen-binding affinity.
Genome scans of DNA variability in humans reveal evidence for selective sweeps outside of Africa.
A multilocus scan of microsatellite variability to identify regions of the human genome that may have been subject to continent-specific hitchhiking events and a disproportionate number of these loci exhibited reduced levels of relative variability in non-African populations alone, suggesting that recent episodes of positive selection have been more prevalent outside of sub-Saharan Africa.