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Chemical Composition of the Essential Oil from the Leaves of Juniperus phoenicea L. from North Africa
TLDR
The results show a number of differences in composition with respect to a previous study of the leaf oils of J. phoenicea (Greece and Spain).
Diterpenoids from Tetraclinis articulata that inhibit various human leukocyte functions.
TLDR
Ten new compounds, eight of them pimarane derivatives (1-8), together with a menthane dimer (9) and a totarane diterpenoid (10), were isolated from the leaves and wood of Tetraclinis articulata using spectroscopic techniques, including 2D NMR spectra.
Oxygenated diterpenes and other constituents from Moroccan Juniperus phoenicea and Juniperus thurifera var. africana.
TLDR
Six new diterpenic acids isolated as their methyl ester derivatives, together with two new isovalerate derivatives of p-methoxycinnamyl alcohol and linalool, were isolated from the leaves of Juniperus thurifera var.
Abietane diterpenes from the cones of Cedrus atlantica.
TLDR
Five new abietanes, three of them isolated as the corresponding acetate derivatives, were isolated from the neutral part of the hexane extract of the cones of Cedrus atlantica collected in Middle Atlas, Morocco by spectroscopic techniques and chemical correlation.
Weakening C-O bonds: Ti(III), a new reagent for alcohol deoxygenation and carbonyl coupling olefination.
TLDR
Investigations detailed herein demonstrate that the formation of either alkoxy- or hydroxy-Ti(III) complexes considerably decreases the energy of activation for C-O bond homolysis, and two new synthetic applications of Nugent's reagent in organic chemistry are described.
Efficient synthesis of the anticancer β-elemene and other bioactive elemanes from sustainable germacrone.
TLDR
Highly efficient preparations of anticancer β-elemene and other bioactive elemanes were carried out using the natural product germacrone as a renewable starting material and an enantioselective approach to these molecules is also described.
First synthesis of the antifungal oidiolactone C from trans-communic acid: cytotoxic and antimicrobial activity in podolactone-related compounds.
TLDR
The synthesis of the fungicide oidiolactone C starting from diterpenic trans-communic acid was carried out with an overall yield of 11.7%, and the highest cytotoxic activity was found in dienic dilactones with ether-type substitutions on C-17.
Total synthesis of (+)-seco-C-oleanane via stepwise controlled radical cascade cyclization.
TLDR
An asymmetric concise total synthesis of the (+)-seco-C-oleanane 1 was accomplished using a stepwise regio- and stereocontrolled catalytic radical polyene cascade cyclization from preoleanatetraene oxide, a process mediated by Cp(2)TiCl.
Reductive coupling of terpenic allylic halides catalyzed by Cp2TiCl: a short and efficient asymmetric synthesis of onocerane triterpenes.
TLDR
Titanocene chloride catalyzes the regioselective alpha,alpha'-homocoupling of terpenic allylic halides, and evidence is presented for eta1-allyltitanium species being involved in the coupling.
Unusually cyclized triterpenes: occurrence, biosynthesis and chemical synthesis.
The biosynthetic origin of most of triterpenes lies in cascade cyclizations and rearrangements of the acyclic precursors squalene (S) and 2,3-oxidosqualene (OS), processes leading to tetra- and
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