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Involvement of Panton-Valentine leukocidin-producing Staphylococcus aureus in primary skin infections and pneumonia.
- G. Lina, Y. Piémont, J. Etienne
- Medicine, BiologyClinical infectious diseases : an official…
- 1 November 1999
Panton-Valentine leukocidin genes were detected in 93% of strains associated with furunculosis and in 85% of those associated with severe necrotic hemorrhagic pneumonia (all community-acquired), and it appears that PVL is mainly associated with nec rotic lesions involving the skin or mucosa.
Comparison of community- and health care-associated methicillin-resistant Staphylococcus aureus infection.
It is suggested that most community-associated MRSA strains did not originate in health care settings, and that their microbiological features may have contributed to their emergence in the community.
Community-Acquired Methicillin-Resistant Staphylococcus aureus Carrying Panton-Valentine Leukocidin Genes: Worldwide Emergence
Analysis of CA-MRSA isolates from the United States, France, Switzerland, Australia, New Zealand, and Western Samoa indicated distinct genetic backgrounds associated with each geographic origin, although predominantly restricted to the agr3 background.
Relationships between Staphylococcus aureus Genetic Background, Virulence Factors, agr Groups (Alleles), and Human Disease
The agr group may reflect an ancient evolutionary division of S. aureus in terms of this species’ fundamental biology, and the results do not show a direct role of the agr type in the type of human disease caused by S.Aureus.
Association between Staphylococcus aureus strains carrying gene for Panton-Valentine leukocidin and highly lethal necrotising pneumonia in young immunocompetent patients
Combination of Multiplex PCRs for Staphylococcal Cassette Chromosome mec Type Assignment: Rapid Identification System for mec, ccr, and Major Differences in Junkyard Regions
The SCCmec type assignments were identical to those made with a PCR system that uses numerous primer pairs to identify genes or gene alleles, and the system of six M-PCRs is thus a convenient and reliable method for typing S CCmec elements.
Evidence in the Legionella pneumophila genome for exploitation of host cell functions and high genome plasticity
The genome reflects the history and lifestyle of L. pneumophila, a human pathogen of macrophages that coevolved with fresh-water amoebae, and encode eukaryotic-like proteins or motifs that are predicted to modulate host cell functions to the pathogen's advantage.
Distribution of Genes Encoding Resistance to Macrolides, Lincosamides, and Streptogramins among Staphylococci
- G. Lina, Alain Quaglia, M. Reverdy, R. Leclercq, F. Vandenesch, J. Etienne
- Biology, MedicineAntimicrobial Agents and Chemotherapy
- 1 May 1999
Resistance to macrolides, lincosamides, and streptogramins was mainly due to the presence ofermA or ermC genes, which were detected in 259 strains, in particular those resistant to methicillin (78% of the strains).
Changing profile of infective endocarditis: results of a 1-year survey in France.
egc, A Highly Prevalent Operon of Enterotoxin Gene, Forms a Putative Nursery of Superantigens in Staphylococcus aureus
RT-PCR analysis showed that all genes, including seg and sei, belong to an operon, designated theEnterotoxin gene cluster (egc), identifying egc as a putative nursery of enterotoxin genes.