Share This Author
Gene Ontology: tool for the unification of biology
The goal of the Gene Ontology Consortium is to produce a dynamic, controlled vocabulary that can be applied to all eukaryotes even as knowledge of gene and protein roles in cells is accumulating and changing.
Gene Ontology Consortium: The Gene Ontology (GO) database and informatics resource
The Gene Ontology (GO) project provides structured, controlled vocabularies and classifications that cover several domains of molecular and cellular biology and are freely available for community use in the annotation of genes, gene products and sequences.
Genealogies of mouse inbred strains
It is proposed that all genealogical and genetic data on inbred strains be submitted to a common electronic database to ensure this valuable information resource is preserved and used efficiently.
The Human Phenotype Ontology project: linking molecular biology and disease through phenotype data
The updated HPO database is described, which provides annotations of 7,278 human hereditary syndromes listed in OMIM, Orphanet and DECIPHER to classes of the HPO, allowing integration of existing datasets and interoperability with multiple biomedical resources.
The Mammalian Phenotype Ontology as a tool for annotating, analyzing and comparing phenotypic information
The Mammalian Phenotype (MP) Ontology enables robust annotation of mammalian phenotypes in the context of mutations, quantitative trait loci and strains that are used as models of human biology and…
The Mouse Genome Database (MGD): mouse biology and model systems
Improvements in MGD described here include the association of gene trap data with mouse genes and a new batch query capability for customized data access and retrieval.
Creating the gene ontology resource: design and implementation.
- J. Blake, J. Corradi, J. Eppig, D. Hill, J. Richardson, M. Ringwald
- Biology, Computer ScienceGenome research
The Gene Ontology project seeks to provide a set of structured vocabularies for specific biological domains that can be used to describe gene products in any organism, which includes building three extensive ontologies to describe molecular function, biological process, and cellular component.
The Mouse Genome Database (MGD): facilitating mouse as a model for human biology and disease
A new addition to MGD, the Human–Mouse: Disease Connection, allows users to explore gene–phenotype–disease relationships between human and mouse, and MGD has also updated search paradigms for phenotypic allele attributes, incorporated incidental mutation data, added a module for display and exploration of genes and microRNA interactions and adopted the JBrowse genome browser.
The mammalian phenotype ontology: enabling robust annotation and comparative analysis
A tool, the Mammalian Phenotype (MP) ontology, is described for classifying and organizing phenotypic information related to the mouse and other mammalian species and aids in the discovery of candidate disease genes and molecular signaling pathways.
Mouse Genome Database (MGD)-2017: community knowledge resource for the laboratory mouse
The Mouse Genome Database (MGD) provides a highly integrated and highly curated system offering a comprehensive view of current knowledge about mouse genes, genetic markers and genomic features as well as the associations of those features with sequence, phenotypes, functional and comparative information, and their relationships to human diseases.