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Studies on ectopic ACTH‐producing tumors. II. Clinical and biochemical features of 30 cases
- H. Imura, S. Matsukura, Masuhisa Nakamura
- Medicine, BiologyCancer
- 1 May 1975
The results indicate that there exist ectopic ACTH‐producing tumors without clinical and biochemical sequelae of excess hormone, and in some of the tumor extracts studied, MSH and CRF‐like activities and serotonin were detected, suggesting that multiple hormone production is not uncommon in ectopicACTH‐ producing tumors.
Biological activity of des-asp1-angiotensin II (angiotensin III) in man.
- T. Kono, F. Oseko, S. Shimpo, M. Nanno, J. Endo
- Biology, MedicineThe Journal of clinical endocrinology and…
- 1 December 1975
Effects of des-asp1-angiotensin II (angioten III) on blood pressure and aldosterone secretion were examined in man and results are consistent with those previously reported by other investigators in animals.
Clinical Value of Sialyl Tn Antigen in Patients With Gynecologic Tumors
- M. Inoue, H. Ogawa, O. Tanizawa, K. Karino, J. Endo
- Medicine, BiologyObstetrics and Gynecology
- 1 June 1990
The current findings demonstrate that the lack of tumor specificity of sialyl Tn antigen limits its diagnostic value in gynecologic malignancies, but that serial measurement of this antigen appears to be useful for monitoring patients and evaluating therapy.
Biological activity of des-Asp1-angiotensin I in man.
- T. Kono, F. Ikeda, F. Oseko, H. Imura, J. Endo
- Biology, MedicineThe Journal of clinical endocrinology and…
- 1980
Results indicate that in man, as in animals, a rise in blood pressure and an increase in plasma aldosterone concentration after an infusion of des-Asp1-AI are entirely due to the actions of AIII converted from this nonapeptide.
Effects of chronic bromocriptine-induced hypoprolactinemia on plasma testosterone responses to human chorionic gonadotropin stimulation in normal men.
- F. Oseko, A. Nakano, K. Morikawa, J. Endo, A. Taniguchi, T. Usui
- Medicine, BiologyFertility and sterility
- 1 February 1991
Effects of angiotensin I-converting enzyme inhibitor, SQ 14225, in nomal men.
It was concluded that complete blockade and partial inhibition of AI conversion by 100 mg of oral SQ 14225 lasted for about 2.5 and 6.5 hr, respectively and that BP rise, PRA suppression and aldosterone stimulation after AI infusion were entirely due to the actions of angiotensin II converted from AI.
Effects of a new angiotensin-converting enzyme inhibitor, MK 421, in normal men and patients.
It is concluded that MK 421 is a strong and long-acting antihypertensive drug and its clinical application seems very useful for the treatment of hypertension.
Suppression of captopril-induced increase in plasma renin activity by des-Asp1-,Ileu8-angiotensin II in man.
- T. Kono, F. Ikeda, F. Oseko, H. Imura, J. Endo
- Medicine, BiologyThe Journal of clinical endocrinology and…
- 1 February 1981
One hundred milligrams of oral captopril (SQ 14225) caused a significant increase in PRA and a significant decrease in plasma aldosterone (PA) in five normal men and five hypertensive patients. Blood…
Biological activity of des-Asp1-,Ileu8-angiotensin II (Ileu8-angiotensin III) in man.
- T. Kono, F. Oseko, F. Ikeda, M. Nanno, J. Endo
- Medicine, BiologyThe Journal of clinical endocrinology and…
- 1 October 1976
Results indicate that in man AIIIA has no pressor action and no antagonistic effect onPressor action of AII but has PRA-lowering and aldosterone-stimulating effects.
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