Lithium and the kidney: an update
- D. Waller, J. Edwards
- MedicinePsychological Medicine
- 1 November 1989
It is a little over a decade since Hestbech et al. (1977) reported histological changes in renal biopsy specimens taken from patients who had been treated with lithium. The more recent studies are…
Systematic Review and Guide to Selection of Selective Serotonin Reuptake Inhibitors
- J. Edwards, I. Anderson
- Psychology, MedicineDrugs
- 1 April 1999
Fluoxetine may not be the drug of first choice for patients in whom a rapid antidepressant effect is important or for those who are agitated, but it may have advantages over other SSRIs in patients who are poorly compliant with treatment and those who have previously had troublesome discontinuation symptoms.
Potentially hazardous drug interactions with psychotropics
- B. Chadwick, D. Waller, J. Edwards
- Medicine
- 1 November 2005
The most serious interactions with psychotropics result in profound sedation, central nervous system toxicity, large changes in blood pressure, ventricular arrhythmias, an increased risk of dangerous side-effects or a decreased therapeutic effect of one of the interacting drugs.
Psychiatric aspects of civilian disasters.
- J. Edwards
- Medicine, PsychologyBritish medical journal
- 17 April 1976
In introducing psychiatry into disaster planning and relief work it should not be seen as yet another example of trying to "psychiatrise" all the problems of the world but as a means of increasing awareness of and sensitivity to the way people react to extreme environmental stress.
Controlled Trial of Sulpiride in Chronic Schizophrenic Patients
- J. Edwards, J. Alexander, M. S. Alexander, A. Gordon, T. Zutchi
- Psychology, MedicineBritish Journal of Psychiatry
- 1 December 1980
The results show that sulpiride has neuroleptic properties and a spectrum of therapeutic activity similar to that of trifluoperazine.
Physical assaults in a psychiatric unit of a general hospital.
- J. Edwards, D. Jones, W. Reid, C. Chu
- Psychology, MedicineAmerican Journal of Psychiatry
- 1988
The assaultive group contained a significantly higher proportion of schizophrenic patients than did the control group and significantly larger numbers of patients from lower socioeconomic classes, patients admitted involuntarily under a section of the Mental Health Act, and patients with a history of assaults.
THE SIDE-EFFECTS OF ANTIPSYCHOTIC DRUGS. I. CNS AND NEUROMUSCULAR EFFECTS
- T. Barnes, J. Edwards
- Psychology, Medicine
- 1993
Haematological safety of antipsychotic drugs
- RL Hall, A. Smith, J. Edwards
- MedicineExpert Opinion on Drug Safety
- 1 July 2003
The authors review the haematological adverse effects and safety of antipsychotic drugs and present a strategy for prevention.
Prescription-Event Monitoring of 10401 Patients Treated with Fluvoxamine
- J. Edwards, W. Inman, L. Wilton, G. Pearce
- Medicine, PsychologyBritish Journal of Psychiatry
- 1 March 1994
Fuvoxamine was shown to be a safe drug and no unexpected or previously undetected drug-related events were encountered, but there was a relatively high incidence of gastro-intestinal symptoms, but other adverse reactions often encountered during treatment with tricyclic antidepressants were not frequently reported.
Prescription-Event Monitoring of 10 895 Patients Treated with Alprazolam
- J. Edwards, W. Inman, G. Pearce, N. Rawson
- Medicine, PsychologyBritish Journal of Psychiatry
- 1 March 1991
The main events reported during treatment, albeit infrequently, were drowsiness and depression, although depression is more likely to be due to the disorder being treated than to the drug.
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