J. Edwards

Publications117
h-index21
Citations1,316
Highly Influential Citations27
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Lithium and the kidney: an update.
It is a little over a decade since Hestbech et al. (1977) reported histological changes in renal biopsy specimens taken from patients who had been treated with lithium. The more recent studies are… Expand
Systematic Review and Guide to Selection of Selective Serotonin Reuptake Inhibitors
TLDR
Fluoxetine may not be the drug of first choice for patients in whom a rapid antidepressant effect is important or for those who are agitated, but it may have advantages over other SSRIs in patients who are poorly compliant with treatment and those who have previously had troublesome discontinuation symptoms. Expand
Psychiatric aspects of civilian disasters.
  • J. Edwards
  • Medicine
  • British medical journal
  • 17 April 1976
TLDR
In introducing psychiatry into disaster planning and relief work it should not be seen as yet another example of trying to "psychiatrise" all the problems of the world but as a means of increasing awareness of and sensitivity to the way people react to extreme environmental stress. Expand
Potentially hazardous drug interactions with psychotropics
TLDR
The most serious interactions with psychotropics result in profound sedation, central nervous system toxicity, large changes in blood pressure, ventricular arrhythmias, an increased risk of dangerous side-effects or a decreased therapeutic effect of one of the interacting drugs. Expand
Controlled trial of sulpiride in chronic schizophrenic patients.
TLDR
The results show that sulpiride has neuroleptic properties and a spectrum of therapeutic activity similar to that of trifluoperazine. Expand
Physical assaults in a psychiatric unit of a general hospital.
TLDR
The assaultive group contained a significantly higher proportion of schizophrenic patients than did the control group and significantly larger numbers of patients from lower socioeconomic classes, patients admitted involuntarily under a section of the Mental Health Act, and patients with a history of assaults. Expand
THE SIDE-EFFECTS OF ANTIPSYCHOTIC DRUGS. I. CNS AND NEUROMUSCULAR EFFECTS
TLDR
This chapter reviews the neuropsychiatric adverse effects that are associated with these drugs, principally the consequences of their actions on the autonomic system, effects on cognition and behavior, epileptogenic effects, the acute extra-pyramidal phenomena and the late-onset movement disorders, such as tardive dyskinesia. Expand
Prescription-event monitoring of 10,401 patients treated with fluvoxamine.
TLDR
Fuvoxamine was shown to be a safe drug and no unexpected or previously undetected drug-related events were encountered, but there was a relatively high incidence of gastro-intestinal symptoms, but other adverse reactions often encountered during treatment with tricyclic antidepressants were not frequently reported. Expand
Haematological safety of antipsychotic drugs
TLDR
The authors review the haematological adverse effects and safety of antipsychotic drugs and present a strategy for prevention. Expand
Renal function during lithium treatment.
TLDR
Renal function tests were performed in 101 unselected patients who had been on lithium for two weeks to 12 years, suggesting that prolonged use of neuroleptics, particularly in patients treated with lithium, may be responsible for an irreversible reduction in urine concentrating ability. Expand
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