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Molecular cloning and characterization of two novel human renal organic anion transporters (hOAT1 and hOAT3).
The cloned organic anion transporters from rat, mouse, and winter flounder (rOAT1, mOAT1, fROAT) mediate the coupled exchange of alpha-ketoglutarate with multiple organic anions, includingExpand
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Molecular cloning and functional characterization of KCC3, a new K-Cl cotransporter.
We isolated and characterized a novel K-Cl cotransporter, KCC3, from human placenta. The deduced protein contains 1,150 amino acids. KCC3 shares 75-76% identity at the amino acid level with human,Expand
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Molecular characterization of two novel transporters from human and mouse kidney and from LLC-PK1 cells reveals a novel conserved family that is homologous to bacterial and Aspergillus nucleobase
Nucleobase transport is important for the metabolism of nucleic acids and antiviral and antineoplastic drugs. This transport has been functionally described in several mammalian cells but has notExpand
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Conserved ETS Domain Arginines Mediate DNA Binding, Nuclear Localization, and a Novel Mode of bZIP Interaction*♦
The DNA-binding ETS transcription factor Spi-1/PU.1 is of central importance in determining the myeloid-erythroid developmental switch and is required for monocyte and osteoclast differentiation.Expand
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Molecular cloning and functional characterization of KCC 3 , a new KCl cotransporter
JOANNE E. RACE,1 FADI N. MAKHLOUF,1,2 PAUL J. LOGUE,2 FREDERICK H. WILSON,3 PHILIP B. DUNHAM,2 AND ELI J. HOLTZMAN1,4 1Renal Division, Department of Medicine, and 4Department of Biochemistry andExpand
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Inhibition of IL-1beta transcription by peptides derived from the hCMV IE2 transactivator.
The immediate early (IE) proteins of human cytomegalovirus (hCMV) have diverse roles in directing viral and host cell transcription. Among these is the ability of IE2 to induce transcription of theExpand
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Molecular cloning and functional characterization of KCC3, a new K-Cl cotransporter.
We isolated and characterized a novel K-Cl cotransporter, KCC3, from human placenta. The deduced protein contains 1,150 amino acids. KCC3 shares 75-76% identity at the amino acid level with human,Expand