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Evidence that nicotine acetylcholine receptors are not the main targets of cotinine toxicity.
The toxicity of nicotine, cotinine and their mixtures was studied in Mus musculus mice as well their effects on growth after repetitive administration to young mice. The affinity constants of the twoExpand
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Plasma malonaldehyde levels during myocardial infarction.
Abstract Malonaldehyde levels were determined in plasma from patients with myocardial infarction. Patients had significantly elevated mean values when compared with normal subjects. Furthermore, inExpand
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Nicotine Is More Efficient than Cotinine at Passing the Blood–Brain Barrier in Rats
Abstract1. Nicotine and its main metabolite, cotinine, were reported to have distinct behavioral activities in mammals.2. In this study, cotinine was synthesized without detectable nicotineExpand
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Isolation and Microsequencing of a Novel Cotinine Receptor
AbstractSUMMARY 1. Nicotine and its main derivative, cotinine, are reported to have distinct central activities in mammals. In this study, the cotinine receptor was separated by biochemicalExpand
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Influence of dicarboxylic phosphatidylcholines on the stability and phase transition of phosphatidylcholine liposomes.
The effect of dicarboxylic phosphatidylcholines (glutaryl phosphatidylcholine) on the stability and phase transition of phosphatidylcholine liposomes is examined by using liposomes prepared with eggExpand
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Inhibition of lecithin:cholesterol acyltransferase in human plasma by dicarboxylic lecithins.
The effect of dicarboxylic lecithins on the lecithin:cholesterol acyltransferase [LCAT] activity was studied with a partially purified preparation [approximately 24-fold]. The presence ofExpand
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Effect of nicotine and cotinine on the susceptibility to in vitro oxidation of LDL in healthy non smokers and smokers.
Cigarette smoke of which the major component is nicotine plays an important role in the development of cardiovascular diseases. To study the effect of in vitro incubation of LDL with nicotine and itsExpand
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Influence of dicarboxylic phosphatidylcholines on phosphatidylcholine liposomes as revealed by gel chromatography and electron microscopy.
The effect of dicarboxylic phosphatidylcholines (glutarylphosphatidylcholine) on the structural changes of phosphatidylcholine liposomes is examined by using multilamellar liposomes prepared with eggExpand
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A qualitative study of normal leukocyte antigens of human leukemic leukoblasts.
Twelve leukocyte antigens have been determined by the method of cytotoxicity in vitro on leukoblasts from 38 patients with acute leukemia, using two batteries of isoimmune human sera. None of theseExpand
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Affinity chromatography of arterial lysosomal cholesterol ester hydrolase.
The glycoproteic nature of rabbit aortic lysosomal cholesterol ester hydrolase has been demonstrated by affinity chromatography on Concanavalin A-Sepharose. After chromatography, the enzyme lacksExpand
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