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HIV-1 infection alters gene expression in adipose tissue, which contributes to HIV- 1/HAART-associated lipodystrophy.
BACKGROUND The aetiopathogenic bases of HIV-l-/highly active antiretroviral treatment (HAART)-associated lipodystrophy (HALS) are poorly known, but this syndrome indicates that adipose tissue isExpand
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Human dendritic cell activities are modulated by the omega‐3 fatty acid, docosahexaenoic acid, mainly through PPARγ:RXR heterodimers: comparison with other polyunsaturated fatty acids
There is accumulating evidence that omega‐3 fatty acids may modulate immune responses. When monocytes were differentiated to dendritic cells (DCs) in the presence of docosahexaenoic acid (DHA), theExpand
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Differential gene expression indicates that ‘buffalo hump’ is a distinct adipose tissue disturbance in HIV-1-associated lipodystrophy
Objective:To elucidate the molecular basis of the progressive enlargement of dorso-cervical adipose tissue, the so-called ‘buffalo hump’, that appears in a sub-set of patients withExpand
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Switching to nevirapine decreases insulin levels but does not improve subcutaneous adipocyte apoptosis in patients with highly active antiretroviral therapy-associated lipodystrophy.
Subcutaneous adipocyte apoptosis occurs in lipotrophic areas of patients with highly active antiretroviral therapy (HAART)-associated lipodystrophy. Fourteen patients with HAART-associatedExpand
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In Vitro Cytotoxicity and Mitochondrial Toxicity of Tenofovir Alone and in Combination with Other Antiretrovirals in Human Renal Proximal Tubule Cells
ABSTRACT We assessed the in vitro toxicity of tenofovir (TFV) and compared it with those of zidovudine (AZT), didanosine (ddI), ritonavir (RTV), and lopinavir (LPV) alone and in combination in humanExpand
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El aprendizaje cooperativo
Much has been written and yet much is still to be written on cooperative learning (CL). This article, rather than explaining what CL is, tries to provide a set of elements that, by the light ofExpand
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Differential effects of efavirenz and lopinavir/ritonavir on human adipocyte differentiation, gene expression and release of adipokines and pro-inflammatory cytokines.
In the present study, a comparative assessment of the effects of efavirenz (EFV) and lopinavir/ritonavir (LPV/r; 4:1) on human adipocytes in culture has been performed. Human pre-adipocytes wereExpand
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Tumour necrosis factor alpha in fat redistribution syndromes associated with combination antiretroviral therapy in HIV‐1‐infected patients: potential role in subcutaneous adipocyte apoptosis
Background  The pathogenesis of fat redistribution syndromes (FRS) observed in the setting of highly active antiretroviral therapy (HAART) for the treatment of HIV‐1‐infection remains elusive. AExpand
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Demencia no detectada y utilización de los servicios sanitarios: implicaciones para la atención primaria
Objetivo Estimar la proporcion de casos de demencia detectados en personas mayores de 70 anos que residen en sus domicilios y describir la utilizacion de los servicios sanitarios y sociales que hacenExpand
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Effects of Rilpivirine on Human Adipocyte Differentiation, Gene Expression, and Release of Adipokines and Cytokines
ABSTRACT Rilpivirine is a nonnucleoside reverse transcriptase inhibitor (NNRTI) recently developed as a drug of choice for initial antiretroviral treatment of HIV-1 infection. Disturbances in lipidExpand
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