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Generation of tissue-specific and promiscuous HLA ligand databases using DNA microarrays and virtual HLA class II matrices
Most pockets in the human leukocyte antigen–group DR (HLA-DR) groove are shaped by clusters of polymorphic residues and, thus, have distinct chemical and size characteristics in different HLA-DRExpand
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Intestinal cytokine response after gut ischemia: role of gut barrier failure.
OBJECTIVE To investigate the effect of intestinal ischemia with and without a reperfusion injury on intestinal cytokine production and gut permeability. SUMMARY BACKGROUND DATA In humans and inExpand
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Downregulation of E-cadherin by hepatitis B virus X antigen in hepatocellullar carcinoma
Hepatitis B virus (HBV)-encoded X antigen (HBxAg) contributes to the development of hepatocellular carcinoma (HCC). A frequent characteristic of HCC is reduced or absent expression of the cellExpand
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The novel human endogenous retrovirus‐related gene, psiTPTE22‐HERV, is silenced by DNA methylation in cancers
The psiTPTE22 gene has been designated as a TPTE pseudogene. Our study found that the 5′ part of psiTPTE22 has no sequence similarity to TPTE and contains a 3.8‐kb human endogenous retrovirus (HERV)Expand
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Maturation of pig oocytes in vivo and in vitro.
In this review the concept that the origins of embryonic failure occur during oocyte development is explored. The four factors that determine oocyte viability, namely a normal growth phase, adequateExpand
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Comparison of plasma cytokine levels in rats subjected to superior mesenteric artery occlusion or hemorrhagic shock.
The overall goal of this study was to compare the effects of systemic hypotension (hemorrhagic shock) versus local gut ischemia (superior mesenteric artery (SMA) occlusion) on cytokine production andExpand
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Expression and functional significance of CDC25B in human pancreatic ductal adenocarcinoma
Pancreatic ductal adenocarcinoma (PDAC) is one of the leading causes of cancer-related deaths. Deregulation of cell-cycle control is thought to be a crucial event in malignant transformation, andExpand
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Alterations in intestinal bacterial flora modulate the systemic cytokine response to hemorrhagic shock.
To test the hypothesis that the resident gut flora plays an active role in modulating the cytokine response to hemorrhagic shock, plasma levels of interleukin-6 (IL-6) and tumor necrosis factor (TNF)Expand
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Computational dissection of tissue contamination for identification of colon cancer‐specific expression profiles
Microarray profiles of bulk tumor tissues reflect gene expression corresponding to malignant cells as well as to many different types of contaminating normal cells. In this report, we assess theExpand
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Identification of a novel human endogenous retrovirus and promoter activity of its 5' U3.
Up-regulation of human endogenous retroviruses (HERVs) sometimes occurs in cancer. This study identifies a novel HERV (HERV-HX) in colon tumor tissues, which is an H family HERV (HERV-H) elementExpand
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