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  • John Charles Jennette, R. Richard Pittsboro Tidwell, J. Dieter Geratz, David H. Bing, Ronald J. Falk
  • Biology, Medicine
  • The American journal of pathology
  • 1987 (First Publication: 1 June 1987)
  • Proteases are involved in the pathogenesis of inflammatory diseases by participating in the activation of mediator systems and by producing proteolytic tissue injury. Homeostatic control ofExpand
  • G B Witkin, Frederic B. Askin, J. Dieter Geratz, Robert Lee Reddick
  • Biology, Medicine
  • International journal of gynecological pathology…
  • 1987 (First Publication: 1 June 1987)
  • A 71-year-old woman who presented with severe vaginal bleeding was found to have a uterine angiosarcoma after total abdominal hysterectomy and bilateral salpingo-oophorectomy. The diagnosis wasExpand
  • R. Richard Pittsboro Tidwell, Susan Kilgore Jones, J. Dieter Geratz, Kwasi A. Ohemeng, Michael Cory, James Edwin Hall
  • Chemistry, Medicine
  • Journal of medicinal chemistry
  • 1990 (First Publication: 1 April 1990)
  • A series of 33 analogues of the anti-Pneumocystis carinii drug 1,5-bis(4-amidinophenoxy)pentane (pentamidine) was synthesized for screening against a rat model of P. carinii pneumonia (PCP).Expand
  • R. Richard Pittsboro Tidwell, J. Dieter Geratz, Otto Dann, Gerda Volz, Dieter Zeh, Heinz Loewe
  • Chemistry, Medicine
  • Journal of medicinal chemistry
  • 1978 (First Publication: 1 July 1978)
  • A series of 62 diarylamidine derivatives was evaluated for their antiproteolytic activity. In all but two of the compounds one or both of the amidino-substituted aryl moieties was either an indole orExpand
  • R. Richard Pittsboro Tidwell, William P. Webster, Sammy Ray Shaver, J. Dieter Geratz
  • Chemistry, Medicine
  • Thrombosis research
  • 1980 (First Publication: 1 August 1980)
  • Abstract In our series of synthetic inhibitors of arginine-specific esteroproteases we have identified 1,2-di(5-amidino-2-benzofuranyl)ethane (DABE) as a preferential inhibitor of bovine factor XaExpand
  • J. Dieter Geratz, Mei Chin Cheng, R. Richard Pittsboro Tidwell
  • Medicine, Chemistry
  • Journal of medicinal chemistry
  • 1976 (First Publication: 1 May 1976)
  • A series of novel aromatic diamidines was synthesized and evaluated for antiproteolytic activity. The compounds were distignuished by inclusion of an aromatic ring structure--either benzene orExpand