J. Dervan

Publications
Influence

Roles of divalent metal ions in flap endonuclease–substrate interactions

M. Feng, Dipak Patel, +4 authors J. Sayers
Chemistry, Medicine
Nature Structural &Molecular Biology
11 April 2004

Flap endonucleases (FENs) have essential roles in DNA processing. They catalyze exonucleolytic and structure-specific endonucleolytic DNA cleavage reactions. Divalent metal ions are essential… Expand

Interactions of mutant and wild-type flap endonucleases with oligonucleotide substrates suggest an alternative model of DNA binding

J. Dervan, M. Feng, +4 authors J. Sayers
Biology, Medicine
Proceedings of the National Academy of Sciences…
25 June 2002

Previous structural studies on native T5 5′ nuclease, a member of the flap endonuclease family of structure-specific nucleases, demonstrated that this enzyme possesses an unusual helical arch mounted… Expand

DNA binding and hydrolysis catalysed by a flap endonuclease

I. R. Sayers, D. Patel, M. Feng, J. Dervan
Chemistry
1 February 2001

REVISED MODEL OF T5 5' NUCLEASE + DNA

J. Dervan, Min Feng, J. Grasby, P. Artymiuk, T. Ceska, J. Sayers
Chemistry
22 May 2002

Differential binding of Mn(II) to bacteriophage T5 5′ nuclease and vital role of metal site II in exonucleolytic cleavage

M. Feng, I. Hag, J. Dervan, Dipak Patel, L. Allen, J. Sayers
Chemistry
1 February 2001

A new model of DNA binding by bacteriophage T5 exonuclease, a flap endonuclease

J. Dervan, L. Allen, J. Sayers
Chemistry
1 February 2001

A helix-loop-helix region of T5 5′-3′ exonuclease contains residues important for substrate and cofactor binding

J. Dervan, J. Sayers
Chemistry
1 June 1999

TYCO SAFETY PRODUCTS AUTHORIZED GLOBAL SOURCE TAGGING INNOVATION CENTERS

Boca Raton, A. Wolters, Wal-Mart Approved, J. Dervan, O. Blanco
Business
2006

Santiago, Chile (Local Market Only) Felipe Lagos Technical Director Luis Apablaza – UPP Supervisor Alfrredo Barros Errazuriz 1973-Providencia Santiago, Chile 56-2-424-6649 flagos@tycoint.com… Expand

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