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- Publications
- Influence
CD209L (L-SIGN) is a receptor for severe acute respiratory syndrome coronavirus.
- Scott A Jeffers, Sonia M Tusell, +11 authors K. Holmes
- Biology, Medicine
- Proceedings of the National Academy of Sciences…
- 2 November 2004
Angiotensin-converting enzyme 2 (ACE2) is a receptor for SARS-CoV, the novel coronavirus that causes severe acute respiratory syndrome [Li, W. Moore, M. J., Vasilieva, N., Sui, J., Wong, S. K.,… Expand
The diversity and evolutionary relationships of the pregnancy-associated glycoproteins, an aspartic proteinase subfamily consisting of many trophoblast-expressed genes.
- S. Xie, J. Green, +4 authors R. Roberts
- Biology, Medicine
- Proceedings of the National Academy of Sciences…
- 25 November 1997
The pregnancy-associated glycoproteins (PAGs) are structurally related to the pepsins, thought to be restricted to the hooved (ungulate) mammals and characterized by being expressed specifically in… Expand
Alveolar Type II Cells Expressing Jaagsiekte Sheep Retrovirus Capsid Protein and Surfactant Proteins Are the Predominant Neoplastic Cell Type in Ovine Pulmonary Adenocarcinoma
- J. A. Platt, N. Kraipowich, F. Villafañe, J. Demartini
- Biology, Medicine
- Veterinary pathology
- 1 May 2002
Ovine pulmonary adenocarcinoma is caused by jaagsiekte sheep retrovirus. To gain insight into the histogenesis and viral pathogenesis of this neoplasm, the tumor cell phenotypes and differentiation… Expand
A Paradigm for Virus–Host Coevolution: Sequential Counter-Adaptations between Endogenous and Exogenous Retroviruses
- F. Arnaud, M. Caporale, +12 authors M. Palmarini
- Biology, Medicine
- PLoS pathogens
- 1 November 2007
Endogenous retroviruses (ERVs) are remnants of ancient retroviral infections of the host germline transmitted vertically from generation to generation. It is hypothesized that some ERVs are used by… Expand
Epizootic Malignant Catarrhal Fever in Three Bison Herds: Differences from Cattle and Association with Ovine Herpesvirus-2
- P. Schultheiss, J. K. Collins, T. Spraker, J. Demartini
- Biology, Medicine
- Journal of veterinary diagnostic investigation…
- 1 November 2000
Three bison herds in Colorado experienced high mortality from malignant catarrhal fever (MCF). In comparison with cattle, the bison had a more rapidly progressive disease, fewer clinical signs, and… Expand
The exogenous form of Jaagsiekte retrovirus is specifically associated with a contagious lung cancer of sheep.
- M. Palmarini, C. Cousens, +4 authors J. Sharp
- Biology, Medicine
- Journal of virology
- 1 March 1996
Sheep pulmonary adenomatosis ([SPA] ovine pulmonary carcinoma) is a transmissible lung cancer of sheep that has been associated etiologically with a type D- and B-related retrovirus (jaagsiekte… Expand
Jaagsiekte Sheep Retrovirus Proviral Clone JSRVJS7, Derived from the JS7 Lung Tumor Cell Line, Induces Ovine Pulmonary Carcinoma and Is Integrated into the Surfactant Protein A Gene
- J. Demartini, J. Bishop, +5 authors J. Carlson
- Biology, Medicine
- Journal of Virology
- 1 May 2001
ABSTRACT Ovine pulmonary carcinoma (OPC) is a contagious neoplasm of alveolar epithelial type II (ATII) or Clara cells caused by a type D/B chimeric retrovirus, jaagsiekte sheep retrovirus (JSRV).… Expand
Unique long terminal repeat U3 sequences distinguish exogenous jaagsiekte sheep retroviruses associated with ovine pulmonary carcinoma from endogenous loci in the sheep genome.
- J. Bai, R. Zhu, +4 authors J. Demartini
- Biology, Medicine
- Journal of virology
- 1 May 1996
Ovine pulmonary carcinoma (OPC) is a contagious lung cancer of sheep that is presumed to be caused by an exogenous retrovirus of sheep, jaagsiekte sheep retrovirus (JSRV). The sheep genome carries 15… Expand
Retrovirus-associated neoplasms of the respiratory system of sheep and goats. Ovine pulmonary carcinoma and enzootic nasal tumor.
- J. Demartini, D. York
- Biology, Medicine
- The Veterinary clinics of North America. Food…
- 1 March 1997
As retrovirus-induced neoplasms of the respiratory epithelium of sheep and goats, OPC and ENT rank as economically important diseases in many countries of the world. They are also important as models… Expand
Lung cancer induced in mice by the envelope protein of jaagsiekte sheep retrovirus (JSRV) closely resembles lung cancer in sheep infected with JSRV
- S. Wootton, M. Metzger, +4 authors A. Miller
- Biology, Medicine
- Retrovirology
- 19 December 2006
BackgroundJaagsiekte sheep retrovirus (JSRV) causes a lethal lung cancer in sheep and goats. Expression of the JSRV envelope (Env) protein in mouse lung, by using a replication-defective… Expand