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The Relationship between Leishmaniasis and AIDS: the Second 10 Years
TLDR
Based on the previous experience of 20 years of coinfection in Europe, this review focuses on the management of Leishmania-HIV-coinfected patients in low-income countries where leishmaniasis is endemic.
Spread of Vector-borne Diseases and Neglect of Leishmaniasis, Europe
TLDR
Exotic vector-borne diseases are gaining attention at the expense of leishmaniasis, according to the World Health Organization.
Comparison of Six PCR Methods Using Peripheral Blood for Detection of Canine Visceral Leishmaniasis
TLDR
Comparisons of the sensitivities and reliabilities of different PCR methods for the diagnosis and epidemiological study of canine visceral leishmaniasis using dog blood allow the discussion of the advantages and drawbacks of highly sensitive versus moderately sensitive PCR methods in diagnosis and prevalence studies of CVL.
Evolutionary and geographical history of the Leishmania donovani complex with a revision of current taxonomy
TLDR
A new taxonomy is proposed, in which Leishmania infantum and L.Donovani are the only recognized species of the L. donovani complex, and an evolutionary hypothesis for the origin and dispersal of the species is presented.
The Leishmania genome comprises 36 chromosomes conserved across widely divergent human pathogenic species.
TLDR
All the physical linkage groups constituting the genome of Leishmania infantum have been identified for the first time by hybridization of specific DNA probes to pulsed field gradient-separated chromosomes, suggesting that conservation of the chromosome structure may be critical for this human pathogen.
Geographical distribution and epidemiological features of Old World cutaneous leishmaniasis foci, based on the isoenzyme analysis of 1048 strains
TLDR
A series of 1048 Leishmania strains from Old World cutaneous leishmaniasis foci, isolated between 1981 and 2005, were studied by isoenzyme analysis and the taxonomic status of this taxon was revised.
Environmental risk mapping of canine leishmaniasis in France
TLDR
The existence of two spatial groups of CanL cases are revealed and niche modelling of these two eco-epidemiological patterns was based on environmental variables and led to the first risk map for CanL in France.
Outbreak of cutaneous leishmaniasis in northern Israel.
TLDR
The northern part of this emerging focus of cutaneous leishmaniasis in Israel is distinct from all known L. tropica foci, and P. arabicus is the main vector, and it transmits parasites that are different from other L. Tropica isolates, with respect to antigenic, molecular, and biochemical parameters.
Visceral leishmaniasis in eastern Sudan: parasite identification in humans and dogs; host-parasite relationships.
TLDR
These results, the relative stability of seroprevalence in dogs and the intradomiciliar presence of P. orientalis, known as a vector of VL in Sudan, suggest several hypotheses: (i) man is responsible for the disease in dogs, (ii) the dog is the reservoir ofVL, and (iii) theDog is an intermediate host between a possible sylvatic cycle and the anthroponotic cycle.
Towards multilocus sequence typing of the Leishmania donovani complex: resolving genotypes and haplotypes for five polymorphic metabolic enzymes (ASAT, GPI, NH1, NH2, PGD).
TLDR
PCR-based genotyping could be applied directly to clinical samples or to small volume cultures and in a multilocus sequence typing format, and can be used to detect recombination indirectly and for population genetics studies.
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