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Genome of the marsupial Monodelphis domestica reveals innovation in non-coding sequences
We report a high-quality draft of the genome sequence of the grey, short-tailed opossum (Monodelphis domestica). As the first metatherian (‘marsupial’) species to be sequenced, the opossum provides aExpand
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Genome analysis of the platypus reveals unique signatures of evolution
This corrects the article DOI: 10.1038/nature06936
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Bird-like sex chromosomes of platypus imply recent origin of mammal sex chromosomes.
In therian mammals (placentals and marsupials), sex is determined by an XX female: XY male system, in which a gene (SRY) on the Y affects male determination. There is no equivalent in other amniotes,Expand
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The Evolution of Epigenetic Regulators CTCF and BORIS/CTCFL in Amniotes
CTCF is an essential, ubiquitously expressed DNA-binding protein responsible for insulator function, nuclear architecture, and transcriptional control within vertebrates. The gene CTCF was proposedExpand
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Reconstructing an Ancestral Mammalian Immune Supercomplex from a Marsupial Major Histocompatibility Complex
The first sequenced marsupial genome promises to reveal unparalleled insights into mammalian evolution. We have used theMonodelphis domestica (gray short-tailed opossum) sequence to construct theExpand
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Exceptionally high conservation of the MHC class I-related gene, MR1, among mammals
The major histocompatibility complex (MHC) class I-related gene, MR1, is a non-classical MHC class IA gene and is encoded outside the MHC region. The MR1 is responsible for activation ofExpand
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Recent Assembly of an Imprinted Domain from Non-Imprinted Components
Genomic imprinting, representing parent-specific expression of alleles at a locus, raises many questions about how—and especially why—epigenetic silencing of mammalian genes evolved. We present theExpand
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The Status of Dosage Compensation in the Multiple X Chromosomes of the Platypus
Dosage compensation has been thought to be a ubiquitous property of sex chromosomes that are represented differently in males and females. The expression of most X-borne genes is equalized between XXExpand
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Genomic Restructuring in the Tasmanian Devil Facial Tumour: Chromosome Painting and Gene Mapping Provide Clues to Evolution of a Transmissible Tumour
Devil facial tumour disease (DFTD) is a fatal, transmissible malignancy that threatens the world's largest marsupial carnivore, the Tasmanian devil, with extinction. First recognised in 1996, DFTDExpand
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Genome Sequence of an Australian Kangaroo, Macropus eugenii
The tammar wallaby (Macropus eugenii) is a model marsupial species that has been intensively used for research into various aspects of marsupial biology. Recently, it became one of only threeExpand
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