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Population preference values for treatment outcomes in chronic lymphocytic leukaemia: a cross-sectional utility study
BackgroundGiven that treatments for chronic lymphocytic leukaemia (CLL) are palliative rather than curative, evaluating the patient-perceived impacts of therapy is critical. To date, no utilityExpand
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Do inhaled carbon nanoparticles translocate directly into the circulation in humans?
  • N. Mills, N. Amin, +10 authors D. Newby
  • Medicine, Physics
  • American journal of respiratory and critical care…
  • 15 February 2006
RATIONALE Increased exposure to particulate air pollution (PM(10)) is a risk factor for death and hospitalization with cardiovascular disease. It has been suggested that the nanoparticulate componentExpand
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On-To-Knowledge: Ontology-based Tools for Knowledge Management
Dieter Fensel, Frank van Harmelen, Michel Klein, Hans Akkermans Free University Amsterdam VUA, Division of Mathematics and Informatics De Boelelaan 1081a, NL-1081 HV Amsterdam, The Netherlands http://www.ontoknowledge.org ; contact: dieter@cs.vu.nl and Jeen Broekstra, Christiaan Fluit, Jos van der Meer, AIdministrator. Expand
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Smart Cities' Data: Challenges and Opportunities for Semantic Technologies
How can we innovate smart systems for smart cities, to make data available homogeneously, inexpensively, and flexibly while supporting an array of applications that have yet to exist or be specified?
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Central nervous system relapse of diffuse large B-cell lymphoma in the rituximab era: results of the UK NCRI R-CHOP-14 versus 21 trial
Abstract Background Central nervous system (CNS) relapse of diffuse large B-cell lymphoma (DLBCL) is associated with a dismal prognosis. Here, we report an analysis of CNS relapse for patientsExpand
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Optimal ex vivo expansion of neutrophils from PBSC CD34+ cells by a combination of SCF, Flt3-L and G-CSF and its inhibition by further addition of TPO
BackgroundAutologous mobilised peripheral blood stem cell (PBSC) transplantation is now a standard approach in the treatment of haematological diseases to reconstitute haematopoiesis followingExpand
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New observing modes for the next century
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OntoShare: a knowledge management environment for virtual communities of practice
An ontology-based knowledge sharing system OntoShare and its evaluation as part of a case study is described. RDF(S) is are used to specify and populate an ontology, based on information sharedExpand
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Outcome of elderly patients with diffuse large B-cell lymphoma treated with R-CHOP: results from the UK NCRI R-CHOP14v21 trial with combined analysis of molecular characteristics with the DSHNHL
Abstract Background There is an on-going debate whether 2- or 3-weekly administration of R-CHOP is the preferred first-line treatment for elderly patients with diffuse large B-cell lymphoma (DLBCL).Expand
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