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Histone H3 Thr-3 Phosphorylation by Haspin Positions Aurora B at Centromeres in Mitosis
Location, Location, Location Cell division is orchestrated by a complex signaling pathway that ensures the correct segregation of newly replicated chromosomes to the two daughter cells. The pathwayExpand
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The kinase haspin is required for mitotic histone H3 Thr 3 phosphorylation and normal metaphase chromosome alignment.
Post-translational modifications of conserved N-terminal tail residues in histones regulate many aspects of chromosome activity. Thr 3 of histone H3 is highly conserved, but the significance of itsExpand
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Regulation of mitotic chromosome cohesion by Haspin and Aurora B.
In vertebrate mitosis, cohesion between sister chromatids is lost in two stages. In prophase and prometaphase, cohesin release from chromosome arms occurs under the control of Polo-like kinase 1 andExpand
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Identification of influenza A nucleoprotein as an antiviral target
Influenza A remains a significant public health challenge because of the emergence of antigenically shifted or highly virulent strains. Antiviral resistance to available drugs such as adamantanes orExpand
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Bacillus korlensis sp. nov., a moderately halotolerant bacterium isolated from a sand soil sample in China.
A Gram-positive-staining, rod-shaped, motile, spore-forming and moderately halotolerant bacterium, designated ZLC-26(T), was isolated from a sand soil sample collected from Xinjiang Province, China,Expand
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Phosphorylation of ACAP1 by Akt regulates the stimulation-dependent recycling of integrin beta1 to control cell migration.
Components of intracellular signaling that mediate the stimulation-dependent recycling of integrins are being identified, but key transport effectors that are the ultimate downstream targets remainExpand
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Pontibacter xinjiangensis sp. nov., in the phylum 'Bacteroidetes', and reclassification of [Effluviibacter] roseus as Pontibacter roseus comb. nov.
A novel strain, designated 311-10(T), isolated from soil of Xinjiang, China, was characterized by using a polyphasic taxonomic approach. The isolate was Gram-negative, aerobic, rod-shaped,Expand
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An ACAP1-containing clathrin coat complex for endocytic recycling
Whether coat proteins play a widespread role in endocytic recycling remains unclear. We find that ACAP1, a GTPase-activating protein (GAP) for ADP-ribosylation factor (ARF) 6, is part of a novelExpand
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Pedobacter arcticus sp. nov., a facultative psychrophile isolated from Arctic soil, and emended descriptions of the genus Pedobacter, Pedobacter heparinus, Pedobacter daechungensis, Pedobacter
A Gram-stain-negative, short rod-shaped, motile (by gliding) bacterial strain, designated A12(T), was isolated from tundra soil collected from Ny-Ålesund, in the Arctic region of Norway. TheExpand
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Flavitalea populi gen. nov., sp. nov., isolated from soil of a Euphrates poplar (Populus euphratica) forest.
A novel strain, designated HY-50R(T), isolated from soil of a Euphrates poplar (Populus euphratica) forest in Xinjiang, China, was characterized using a polyphasic taxonomic approach. Cells of theExpand
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