• Publications
  • Influence
Falling asleep at the wheel: Motor vehicle mishaps in persons taking pramipexole and ropinirole
TLDR
A new side effect of the dopamine agonists pramipexole and ropinirole: sudden irresistible attacks of sleep that causes patients to fall asleep while driving, causing accidents.
Elevated plasma homocysteine levels in patients treated with levodopa: association with vascular disease.
TLDR
This is the first report that levodopa-related hyperhomocysteinemia is associated with increased risk for coronary artery disease (CAD), and the findings have implications for the treatment of PD in patients at risk for vascular disease, and potentially for those at risk of dementia and depression.
The nucleus basalis of Meynert in neurological disease: A quantitative morphological study
TLDR
A large series of studies on the nucleus basalis of Meynert (nbM) confirms the marked degeneration of the nbM in Alzheimer's disease, but also places such degeneration into perspective in a spectrum of dementing and nondementing neurological diseases.
The clinical spectrum of unruptured intracranial aneurysms.
TLDR
Acute severe headache, comparable to subarachnoid hemorrhage headache, but without nuchal rigidity, was associated with the following mechanisms: aneurysm thrombosis, localized meningeal inflammation, and unexplained.
Delusional misidentification in association with parkinsonism.
TLDR
Three cases of DMS in patients with Parkinson's disease and dementia, treated with dopaminergic medications, are presented and it is postulated that DMS associated with parkinsonism results from a combination of dopaminaergic psychosis and cognitive dysfunction involving the frontal lobe in particular.
Benzocaine and lidocaine induced methemoglobinemia after bronchoscopy: a case report
TLDR
The patient was continued on 15 L/minute nonrebreathing face mask and subsequent oxygen saturation improved to 92% within two hours and treatment with methylene blue was withheld.
Dimensions of sexual dysfunction in Parkinson disease.
TLDR
The increase in sexual fantasy with greater PD duration suggests that patients with advancing disease remain interested in sex and that sexual dysfunction in PD is clinically relevant in this group.
Stimulus intensity and trace intervals in sensory preconditioning using the CER
Sixty-four rats were given preconditioning training (S1 -S2 pairings) with a trace interval of 0, 2, 5, or 8 sec and an S1 of either strong or mild intensity. Preconditioning was followed by
S‐adenosyl‐methionine improves depression in patients with Parkinson's disease in an open‐label clinical trial
TLDR
Although uncontrolled and preliminary, this study suggests that SAM is well tolerated and may be a safe and effective alternative to the antidepressant agents currently used in patients with Parkinson's disease.
Hypersexuality after pallidal surgery in Parkinson disease.
TLDR
The case of a patient with PD and a history of right pallidotomy who developed a psychiatric syndrome, including prominent hypersexuality, after surgical implantation of a deep brain stimulation electrode in the left globus pallidus demonstrates that patients receiving antiparkinson medication may be at risk for the development of psychiatric sequelae after pallidal surgery.
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