J. D. Griffith

Publications34
h-index16
Citations1,896
Highly Influential Citations43
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Human pharmacology and abuse potential of the analgesic buprenorphine: a potential agent for treating narcotic addiction.
Buprenorphine was evaluated for its abuse potential and utility in treating narcotic addiction. The drug was morphine-like but was 25 to 50 times more potent than morphine and was longer-acting.… Expand
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Contingency management in outpatient methadone treatment: a meta-analysis.
A meta-analysis was conducted on contingency management interventions in outpatient methadone treatment settings. The outcome measure of interest was drug use during treatment, as detected through… Expand
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Cotinine concentrations in semen, urine, and blood of smokers and nonsmokers.
Cotinine levels in the semen, urine, and blood of 88 male smokers and nonsmokers, aged 18 to 35, were analyzed via radioimmunoassay. Detectable cotinine levels were found in all three body fluids,… Expand
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Bupropion: clinical assay for amphetamine-like abuse potential.
Bupropion hydrochloride (100, 200, and 400 mg), d-amphetamine sulfate (15 and 30 mg), and placebo were compared in 13 volunteers who had histories of amphetamine abuse. Each dose was given orally at… Expand
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Dextroamphetamine. Evaluation of psychomimetic properties in man.
Nine informed volunteers having previous experience with self-administered drugs were given small, frequent orally administered doses of dextroamphetamine sulfate. Within five days following… Expand
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A comparison of fenfluramine and amphetamine in man
dl‐Fenfluramine hydrochloride (60, 120, 240 mg), d‐amphetamine sulfate (20, 40 mg), and placebo were compared in 8 postaddict volunteers, each dose given orally in random sequence at weekly intervals… Expand
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Lithium: effects on subjective functioning and morphine-induced euphoria.
The therapeutic usefulness of lithium in decreasing the euphoria and other symptoms associated with manic behavior and the hypothesis of a common final mechanism for elevations in mood have led to… Expand
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Effects of lithium on adrenergic function in man
Lithium is an effective agent in the treatment of mania. Since an abnormality of biogenic amines has been postulated to be a causative factor in mania and depression and since lithium has been found… Expand
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Investigation of the abuse liability of buspirone in alcohol-dependent patients.
By use of the Addiction Research Center Inventory, the Amphetamine Self-Rating Scale, the Single-Dose Questionnaire, and selected physiologic measures (blood pressure, pulse and respiratory rates,… Expand
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Effects of diethylpropion and d‐amphetamine after subcutaneous and oral administration
The effects of diethylpropion were determined and compared with those of d‐amphetamine in 9 subiects using a crossover design. Diethylpropion produced effects qualitatively similar to those of… Expand
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