• Publications
  • Influence
Multiplexed and data-independent tandem mass spectrometry for global proteome profiling.
One of the most important early developments in the field of proteomics was the advent of automated data acquisition routines that allowed high-throughput unattended data acquisition during HPLCExpand
Gold microspheres: a selective technique for producing biologically effective dose enhancement.
PURPOSE To investigate dose enhancement and radiosensitization associated with electrons produced and scattered from gold particles suspended in cells in vitro and with tumour cells growing in vivoExpand
Mapping PARP-1 auto-ADP-ribosylation sites by liquid chromatography-tandem mass spectrometry.
We demonstrate a novel method for the identification of poly(ADP-ribose) polymerase-1 (PARP-1) autopoly(ADP-ribosyl)ation sites that is suited to collision induced dissociation (CID) tandem massExpand
Incorporating clinical measurements of hypoxia into tumor local control modeling of prostate cancer: implications for the alpha/beta ratio.
BACKGROUND AND PURPOSE The recently obtained low value of approximately 1.5 for the alpha/beta of prostate cancer has led us to reexamine the optimal prostate tumor biology parameters, while takingExpand
Letter: Studies on the mechanism of chemical radioprotection by dimethyl sulphoxide.
Incorporating clinical measurements of hypoxia into tumor local control modeling of prostate cancer: Implications for the α/β ratio
Abstract Background and purpose The recently obtained low value of ∼1.5 for the α/β of prostate cancer has led us to reexamine the optimal prostate tumor biology parameters, while taking into accountExpand
Radioprotection by DMSO of mammalian cells exposed to X-rays and to heavy charged-particle beams
SummaryPopulations of G1-phase Chinese hamster cells in stirred suspensions containing various concentrations of DMSO were irradiated with 250 kV X-rays or various heavy charged-particle beams.Expand
Iodine-124-labeled iodo-azomycin-galactoside imaging of tumor hypoxia in mice with serial microPET scanning
Tumor hypoxia, present in many human cancers, can lead to resistance to radiation and chemotherapy, is associated with a more aggressive tumor phenotype and is an independent prognostic factor ofExpand
Oxygen dependency of tumor cell killing in vitro by light-activated Photofrin II.
Asynchronous populations of mouse EMT-6 tumor cells were treated with Photofrin II and exposed to various doses of 630 nm light in slowly stirred suspensions which had been equilibrated with variousExpand
Radiation and high-dose metronidazole in supratentorial glioblastomas.
We used "high-dose" metronidazole, an "in vitro" and "in vivo" specific radiosensitizer of hypoxic cells, in a controlled trial to evaluate possible enhancement of radiation effect in patients withExpand
...
1
2
3
4
5
...