Employing a transgenic animal model to obtain cementoblasts in vitro.
- J. D'Errico, J. Berry, H. Ouyang, C. Strayhorn, J. Windle, M. Somerman
- Biology, MedicineThe Journal of Periodontology
- 2000
This approach for establishing cementoblasts in vitro provides a model to study cementogenesis as required to enhance knowledge of the mechanisms controlling development, maintenance, and regeneration of periodontal tissues.
Commercially-prepared allograft material has biological activity in vitro.
- Y. Shigeyama, J. D'Errico, R. Stone, M. Somerman
- Biology, MedicineThe Journal of Periodontology
- 1 June 1995
The ability of commercial extracts to promote cell proliferation, while significant, was limited and significantly less when compared with similar extracts prepared from freshly obtained bone, while none of the extracts promoted cell migration.
Expression of bone associated markers by tooth root lining cells, in situ and in vitro.
- J. D'Errico, R. L. MacNeil, T. Takata, J. Berry, C. Strayhorn, M. Somerman
- Biology, MedicineBone
- 1 February 1997
Role of two mineral-associated adhesion molecules, osteopontin and bone sialoprotein, during cementogenesis.
- R. L. MacNeil, J. Berry, J. D'Errico, C. Strayhorn, B. Piotrowski, M. Somerman
- BiologyConnective Tissue Research
- 1995
It is suggested that BSP and OPN are intimately involved in the sequence of cellular and molecular events accompanying cementogenesis and that OPN functions as an inhibitor of mineralization during periodontal ligament formation.
Immortalized cementoblasts and periodontal ligament cells in culture.
- J. D'Errico, H. Ouyang, M. Somerman
- Biology, MedicineBone
- 1 July 1999
Functional analysis of bone sialoprotein: identification of the hydroxyapatite-nucleating and cell-binding domains by recombinant peptide expression and site-directed mutagenesis.
- N. L. Harris, K. Rattray, H. Goldberg
- BiologyBone
- 1 December 2000
Protein extracts of dentin affect proliferation and differentiation of osteoprogenitor cells in vitro.
- T. Takata, J. D'Errico, M. Somerman
- Biology, MedicineThe Journal of Periodontology
- 1 November 1998
The results suggest that TGFbeta1 and perhaps other factors in dentin can regulate cell behavior and, therefore, can influence development, remodeling, and regeneration of mineralized tissues.
Localization and Expression of Osteopontin in Mineralized and Nonmineralized Tissues of the Periodontium a
- R. L. MacNEIL, J. Berry, J. D'Errico, C. Strayhorn, M. Somerman
- BiologyAnnals of the New York Academy of Sciences
- 1 August 1995
There is general agreement that OPN is expressed/localized to the root surface during cementogenesis and is also seen throughout the PDL region and the expression/localization of OPN to odontoblasts and its role in dentinogenesis is less apparent.
Isolation of murine cementoblasts: unique cells or uniquely-positioned osteoblasts?
- R. L. MacNeil, J. D'Errico, H. Ouyang, J. Berry, C. Strayhorn, M. Somerman
- Biology, MedicineEuropean Journal of Oral Sciences
- 1998
It is proposed that cells within this heterogeneous population, which express this profile of osteogenic proteins, represent cementoblasts and the availability of a cementoblast cell line will make possible rigorous and controlled in vitro analysis ofThese cells and allow for determination of the unique characteristics of these cells not shared with other cells, particularly osteoblasts.
Response of immortalized murine cementoblasts/periodontal ligament cells to parathyroid hormone and parathyroid hormone-related protein in vitro.
- H. Ouyang, L. McCauley, J. Berry, J. D'Errico, C. Strayhorn, M. Somerman
- Biology, MedicineArchives of Oral Biology
- 1 April 2000
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