J. Cui

Publications106
h-index24
Citations1,881
Highly Influential Citations32
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Z-Ajoene Induces Apoptosis of HL-60 Cells: Involvement of Bcl-2 Cleavage
TLDR
Z-ajoene, a sulfur-rich compound purified from garlic, induced time- and dose-dependent apoptosis in HL-60 cells and involved a reactive oxygen species-dependent pathway leading to caspase-dependent Bcl-2 cleavage.
The cytotoxic activity of ursolic acid derivatives.
Ursolic acid and 2alpha-hydroxyursolic acid isolated from apple peels were found to show growth inhibitory activity against four tumor cell lines, HL-60, BGC, Bel-7402 and Hela. Structural…
New class of potent antitumor acylhydrazone derivatives containing furan.
  • Zining Cui, Y. Li, +4 authors X. Yang
  • Chemistry, Medicine
    European journal of medicinal chemistry
  • 1 December 2010
TLDR
IIf showed great promise as a novel lead compound for further anticancer discovery and was better than doxorubicin against human promyelocytic leukemic cells (HL-60).
Polynuclear diorganotin(IV) complexes with arylhydroxamates: Syntheses, structures and in vitro cytotoxic activities.
TLDR
The polymeric diorganotin/hydroxamato complexes a containing the long carbon chain butyl ligands are the most active ones, and the dependence of the antitumor activity of the complexes on various factors, namely the nuclearity, the organic ligand, the type, position and number of the X ring substituents is also discussed.
Synthesis, crystal structures and in vitro antitumor activities of some organoantimony arylhydroxamates
A series of novel organoantimony arylhydroxamates with the formulae [Ar 3 SbL 2 ] − [HNEt 3 ] + (LH = arylhydroxamic acid; Ar = C 6 H 5 , 4-CH 3 C 6 H 4 , 3-CH 3 C 6 H 4 , 4-ClC 6 H 4 , 4-FC 6 H 4 )…
NO inhibitory guaianolide-derived terpenoids from Artemisia argyi.
TLDR
In in vitro assay, compound 2 exhibited pronounced inhibition on the lipopolysaccharide (LPS)-induced nitric oxide (NO) production in BV-2 microglial cells with an IC50 value of 4.00μM.
Furanodiene, a Natural Product, Inhibits Breast Cancer Growth Both in vitro and in vivo
TLDR
It is concluded that furanodiene suppresses breast cancer cell growth both in vitro and in vivo and could be a new lead compound for breast cancer chemotherapy.
Effect of beta-escin sodium on endothelial cells proliferation, migration and apoptosis.
TLDR
The findings give the evidence that beta-escin sodium might have potential anti-angiogenic activity via its direct effects on ECs through its inhibition of proliferation, migration and apoptosis in human umbilical vein endothelial cells and ECV304 cells.
Cardenolides from Saussurea stella with cytotoxicity toward cancer cells.
TLDR
The first report of cardenolides occurring in a species of the family Asteraceae is reported, isolated from a cytotoxic ethanol extract of the whole dried plants of Saussurea stella.
β‐Escin sodium inhibits inducible nitric oxide synthase expression via downregulation of the JAK/STAT pathway in A549 cells
TLDR
Results demonstrate that β‐escin sodium could downregulate iNOS expression through inhibiting JAK/STAT signaling and p38 MAPK activation in A549 cells and would be useful as a chemopreventive agent or a therapeutic against inflammatory‐associated tumor.
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