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Increased NMDA current and spine density in mice lacking the NMDA receptor subunit NR3A
The NMDA (N -methyl-D-aspartate) subclass of glutamate receptor is essential for the synaptic plasticity thought to underlie learning and memory and for synaptic refinement during development,. It isExpand
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13-cis-retinoic acid suppresses hippocampal cell division and hippocampal-dependent learning in mice.
The active component of the acne drug Accutane is 13-cis-retinoic acid (RA), and it is highly teratogenic for the developing central nervous system. Very little is known, however, regarding theExpand
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A scale for social interest.
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Cdk5 Regulates the Phosphorylation of Tyrosine 1472 NR2B and the Surface Expression of NMDA Receptors
NMDA receptors (NMDARs) are a major class of ionotropic glutamate receptors that can undergo activity-dependent changes in surface expression. Clathrin-mediated endocytosis is a mechanism by whichExpand
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Compartment-specific transcription factors orchestrate angiogenesis gradients in the embryonic brain
Prevailing notions of cerebral vascularization imply that blood vessels sprout passively into the brain parenchyma from pial vascular plexuses to meet metabolic needs of growing neuronal populations.Expand
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Retinoic acid signaling and function in the adult hippocampus.
Retinoic acid (RA) is an essential growth factor, derived from vitamin A, which controls growth by activating specific receptors that are members of the nuclear receptor family of transcriptionalExpand
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Molecular structure of cytoplasmic dynein 2 and its distribution in neuronal and ciliated cells
Cytoplasmic dynein is involved in a wide variety of cellular functions. In addition to the initially characterized form (MAP 1C/dynein 1), a second form of cytoplasmic dynein (dynein 2) has beenExpand
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Distribution of stage-specific neurite-associated proteins in the developing murine nervous system recognized by a monoclonal antibody
A monoclonal antibody, 4D7, obtained with embryonic rat brain as an immunogen, recognizes an epitope on 3 protein species of 150–160, 100– 110, and 80 kDa, present in mouse and rat brain during theExpand
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