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- Influence
Whole genome sequencing of multiple Leishmania donovani clinical isolates provides insights into population structure and mechanisms of drug resistance.
- T. Downing, H. Imamura, +17 authors M. Berriman
- Biology, Medicine
- Genome research
- 1 December 2011
Visceral leishmaniasis is a potentially fatal disease endemic to large parts of Asia and Africa, primarily caused by the protozoan parasite Leishmania donovani. Here, we report a high-quality… Expand
Genomic Insights into the Origin of Parasitism in the Emerging Plant Pathogen Bursaphelenchus xylophilus
- T. Kikuchi, J. Cotton, +19 authors M. Berriman
- Biology, Medicine
- PLoS pathogens
- 1 September 2011
Bursaphelenchus xylophilus is the nematode responsible for a devastating epidemic of pine wilt disease in Asia and Europe, and represents a recent, independent origin of plant parasitism in… Expand
Genome-wide signatures of convergent evolution in echolocating mammals
- J. Parker, G. Tsagkogeorga, +4 authors S. Rossiter
- Biology, Medicine
- Nature
- 7 August 2013
Evolution is typically thought to proceed through divergence of genes, proteins and ultimately phenotypes. However, similar traits might also evolve convergently in unrelated taxa owing to similar… Expand
Tempo and Mode of Diversification of Lake Tanganyika Cichlid Fishes
- J. J. Day, J. Cotton, T. Barraclough
- Biology, Medicine
- PloS one
- 5 March 2008
Background Understanding the causes of disparities in species diversity across taxonomic groups and regions is a fundamental aim in evolutionary biology. Addressing these questions is difficult… Expand
The genome and life-stage specific transcriptomes of Globodera pallida elucidate key aspects of plant parasitism by a cyst nematode
BackgroundGlobodera pallida is a devastating pathogen of potato crops, making it one of the most economically important plant parasitic nematodes. It is also an important model for the biology of… Expand
The Ediacaran emergence of bilaterians: congruence between the genetic and the geological fossil records
- K. Peterson, J. Cotton, J. G. Gehling, D. Pisani
- Biology, Medicine
- Philosophical Transactions of the Royal Society B…
- 27 April 2008
Unravelling the timing of the metazoan radiation is crucial for elucidating the macroevolutionary processes associated with the Cambrian explosion. Because estimates of metazoan divergence times… Expand
Comparative Genomics of the Apicomplexan Parasites Toxoplasma gondii and Neospora caninum: Coccidia Differing in Host Range and Transmission Strategy
- A. Reid, S. Vermont, +20 authors J. Wastling
- Biology, Medicine
- PLoS pathogens
- 1 March 2012
Toxoplasma gondii is a zoonotic protozoan parasite which infects nearly one third of the human population and is found in an extraordinary range of vertebrate hosts. Its epidemiology depends heavily… Expand
Supertrees disentangle the chimerical origin of eukaryotic genomes.
- D. Pisani, J. Cotton, J. McInerney
- Medicine, Biology
- Molecular biology and evolution
- 1 August 2007
Eukaryotes are traditionally considered to be one of the three natural divisions of the tree of life and the sister group of the Archaebacteria. However, eukaryotic genomes are replete with genes of… Expand
Majority-rule supertrees.
- J. Cotton, M. Wilkinson
- Mathematics, Medicine
- Systematic biology
- 1 June 2007
Most supertree methods proposed to date are essentially ad hoc, rather than designed with particular properties in mind. Although the supertree problem remains difficult, one promising avenue is to… Expand
The evolution of color vision in nocturnal mammals
- H. Zhao, S. Rossiter, E. Teeling, Chanjuan Li, J. Cotton, Shuyi Zhang
- Biology, Medicine
- Proceedings of the National Academy of Sciences
- 2 June 2009
Nonfunctional visual genes are usually associated with species that inhabit poor light environments (aquatic/subterranean/nocturnal), and these genes are believed to have lost function through… Expand